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Research Feature
Joncita Todechine, a mother of four who lives on the Navajo Nation, knows all too well what can trigger asthma symptoms in her daughter Ashley. But she didn’t always. She recalls a time in 2013, living in Phoenix and attending medical assistant school, when she rushed her then-three-year-old to the Indian Medical Center. “She was really sick,”...
Showing 10 out of 114 results
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NHLBI in the Press
Researchers identified genes and pathways involved in triggering a hyperinflammatory COVID-19 immune response – starting with platelets – and are studying how inhibiting these pathways may alter clinical outcomes for hospitalized patients.
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NHLBI in the Press
A phase 2 study with 59 patients found fostamatinib, a targeted immune therapy used for a rare bleeding disorder, did not result in more adverse outcomes among adults hospitalized for COVID-19 who required assisted breathing support.
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News Release
The final results of the Clinical Trial of COVID-19 Convalescent Plasma in Outpatients (C3PO) demonstrate that COVID-19 convalescent plasma did not prevent disease progression in a high-risk group of outpatients with COVID-19, when administered within the first week of their symptoms. The trial was stopped in February 2021 due to lack of efficacy...
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NHLBI in the Press
The final results of the Clinical Trial of COVID-19 Convalescent Plasma in Outpatients (C3PO) demonstrate that COVID-19 convalescent plasma did not prevent disease progression in a high-risk group of outpatients with COVID-19.
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NHLBI in the Press
As many as one-fifth of patients hospitalized with severe COVID-19 nationwide who may have benefited from treatment with the anti-inflammatory dexamethasone were not given this treatment during the height of the pandemic, according to a study.
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News Release
A large clinical trial conducted worldwide shows that treating moderately ill hospitalized COVID-19 patients with a full-dose blood thinner reduced their need for organ support, such as mechanical ventilation, and improved their chances of leaving the hospital. However, the use of this treatment strategy for critically ill COVID-19 patients...
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NHLBI in the Press
After studying antibody levels in 328 patients hospitalized for COVID-19, researchers identified patterns associated with severe inflammation and illness, such as the need for assisted breathing support. This research supports larger efforts to develop targeted treatment.
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NHLBI in the Press
After studying biomarkers and stool samples in children who had multisystem inflammatory syndrome in children (MIS-C) or COVID-19, researchers identified a pathway involved in gut permeability that may prolong COVID-19 illness and respond to a therapy that’s being tested for celiac disease.
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NHLBI in the Press
Airway cells from patients with chronic lung diseases are “primed” for infection by coronavirus, resulting in more severe symptoms, poorer outcomes, and a greater likelihood of death, according to a study published in Nature Communications.