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Study shows treatment does no harm, but provides no benefit What A clinical trial to evaluate the safety and effectiveness of hydroxychloroquine for the treatment of adults hospitalized with coronavirus disease 2019 (COVID-19) has been stopped by the National Institutes of Health. A data and safety monitoring board (DSMB) met late Friday and...
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Research Feature
NHLBI expands access to diverse genetic data, creating more possibilities for personalized medicine It was a big moment nearly four years ago when NHLBI’s Trans-Omics for Precision Medicine program (TOPMed) released nearly 9,000 whole genomes to a limited group of researchers. The genomes—complete sets of people’s DNA—were the first the program had...
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Research Feature
A new smartphone app could be a boon for adolescents, young adults When the Food and Drug Administration (FDA) approved the drug hydroxyurea to help reduce the excruciating pain suffered by people with sickle cell disease, the health care community was hopeful. The year was 1998, and the prospect of a drug that could offer significant relief from...
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Research Feature
NHLBI-funded researchers tackle big questions with large study of patients hospitalized with COVID-19 The doctors on the front lines of the coronavirus pandemic may be aware of the health impacts that face survivors of mass shootings or natural disasters, but the highly contagious virus—one of the deadliest in history—is forcing them to grapple...
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Research Feature
In 2014 when the deadly Ebola virus was spreading like wildfire through parts of West Africa, Rear Admiral Richard Childs, M.D., led a team of physicians, nurses, engineers, and safety inspectors to Monrovia, Liberia to help treat the thousands of patients who had been infected. As the chief medical officer for the U.S. Public Health Service (USHPS...
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Research Feature
When doctors diagnosed Mary Douglas-Brown, 69, with breast cancer in 2004, she turned to her congregation at Pilgrim Rest Baptist Church in Washington D.C. for support, only to learn that it did not have a ministry to provide health and lifestyle resources that might help her through her ordeal. So she did what any determined churchgoer would do:...
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Research Feature
Multi-institute NIH study suggests that the HPV vaccine could protect women against new HPV infections after stem cell transplantation The human papillomavirus (HPV) vaccine provides a safe, robust immune response against HPV in reproductive-aged women who have had a stem cell transplant. The results from the small study published in the Journal of...
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Research Feature
Two doctors point the way to better heart health for midlife black women Spend a little time with Marilyn Gaston, M.D., and Gayle Porter, Psy.D., and it’s not hard to guess they’ve been pals for a long time—42 years to be exact. They finish each other’s sentences, can tell you everything about the other’s family and friends. They even live together...
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Research Feature
NIH researchers can maintain image quality from different scanning systems while reducing or avoiding radiation exposure When doctors want detailed images of the lungs, more often than not they turn to chest CT scans . Over the years these scans have been particularly useful in diagnosing lung diseases—so useful, in fact, that in the United States,...
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Research Feature
For much of her life, Sarah Gorman, 71, battled a mysterious illness that left her tired, sleepless, and unable to concentrate. When her symptoms first started in her 20s, she turned to doctors for help. They diagnosed her with depression and referred her to a psychiatrist, but Gorman soon rejected that diagnosis because, she said, she simply did...
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Research Feature
It is the fourth leading cause of death in the United States, affecting nearly 16 million people, but for many Americans, chronic obstructive pulmonary disease, or COPD, still remains a mystery. That’s why in 2017, at the request of Congress, the NHLBI led a year-long, multi-team effort to figure out what it would take to relieve the burden of this...