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Activating a protein in red blood cells may improve anemia and alleviate acute episodes of severe pain for people living with sickle cell disease Swee Lay Thein, M.B., D.Sc., a senior investigator and chief of NHLBI’s Sickle Cell Branch, shares insight into a decade-long research journey that may lead to new ways to help people living with sickle...
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Research Feature
Activating a protein in red blood cells may improve anemia and alleviate acute episodes of severe pain for people living with sickle cell disease Swee Lay Thein, M.B., D.Sc., a senior investigator and chief of NHLBI’s Sickle Cell Branch, shares insight into a decade-long research journey that may lead to new ways to help people living with sickle...
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Research Feature
Through an adaptive research trial, doctors and patients from 30 U.S. study locations are working together to study if five new medications can help patients with severe asthma by altering the underlying biology of this airway disease. As Erin Routh prepares to walk in winter weather, she does more than put on a jacket, hat, and gloves. The 46-year...
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Research Feature
INTRODUCTION: April P. Carson, Ph.D., was recently named director of the Jackson Heart Study (JHS), the largest and longest running study of cardiovascular disease in African Americans. With this appointment, Dr. Carson becomes the first woman to be named director of the study, which is now in its 22nd year. In addition to holding the title of JHS...
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Research Feature
It’s a fact few can dispute: The COVID-19 pandemic has been devastating on Americans. It has caused high rates of death and illness, disrupted nearly every aspect of daily life, and been linked to increased heart disease, lung disease, obesity, and sleep problems. Now, NHLBI-funded researchers say the virus and related stress can also be blamed for...
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Research Feature
New research shows that by tending to their cardiovascular health now, patients can get big benefits during pregnancy and beyond It’s important to keep hearts healthy at every life stage, but how people take care of themselves leading up to and during pregnancy can affect their cardiovascular health for decades. Victoria Pemberton, a nurse and...
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Research Feature
A cell-based look at how the body responds to immune threats may one day help researchers find better treatments for this major U.S. killer For more than a decade, researchers have known that a core component of human immune function – called complement – can influence how the body responds to immune threats. Now researchers from the NIH and around...
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NIH research continues to evaluate how blood thinners and anti-inflammatory medications may strengthen recovery at different points in the life of the virus W. Keith Hoots, M.D., director of the Division of Blood Disorders and Resources (DBDR) at the National Heart, Lung, and Blood Institute (NHLBI), shares insight into how treatments that break up...
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Severe blood clotting in patients has sent researchers in search of answers to optimize treatment and recovery As the virus that causes COVID-19 invades cells and replicates its code for infection, the body’s immune response fights back. However, for some people this can lead to extreme blood clotting – which can increase the risk for heart attack...
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Research Feature
Millions of people in America have been diagnosed with chronic obstructive pulmonary disease (COPD)—the umbrella term for emphysema and chronic bronchitis—and millions more have it and don’t know it. People in rural and other underserved communities are more likely to face higher rates of COPD and worse health outcomes from the disease. And for...
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Research Feature
For 33 years, the NHLBI’s Strong Heart Study has focused on learning why American Indians have one of the highest heart disease rates in the nation—almost double that of the general population. And during that time, it has made important discoveries – confirming, for example, that risk factors like diabetes, high blood pressure, and elevated...