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August 17, 2016

Study Shows Acetaminophen Can Be Tolerated by Young Children With Mild, Persistent Asthma

WHAT: In a study of children with mild, persistent asthma, scientists found that acetaminophen was tolerated without the worsening of asthma, when compared with ibuprofen use. The study, funded by the National Heart, Lung, and Blood Institute’s asthma network (AsthmaNet), appears in the August 18, 2016, issue of the New England Journal of Medicine.

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August 24, 2016 : News Medical

Researchers, led by the National Heart, Lung, and Blood Institute’s Nehal Mehta, found that the prevalence of moderate to severe coronary calcification was the same for patients who have psoriasis and type 2 diabetes. The prevalence of coronary calcification was about five times higher for these two groups when compared to healthy patients. The findings appear in JAMA Dermatology.

August 22, 2016 : NIH News Release

Researchers are reporting that a special human protein, when combined with stem cell therapy, helped repair stroke damage to the brains of mice. The special protein appears to increase the production of nerve cells.  The finding could lead to a new way to help people recover following stroke, the researchers say.  The study, published in Nature Medicine, was funded by the National Institute of Neurological Disorders and Stroke (NINDS), the National Heart, Lung, and Blood Institute (NHLBI), and other institutions.

September 9, 2016
6701 Rockledge Drive, (Conference Room 9100/9104) Bethesda, MD 20892
The severe anemia associated with hematologic disorders such as β thalassemia, myelodysplastic syndrome, and congenital dyserythropoietic anemia, arises from defects in late stage erythroid maturation (dyserythropoiesis). In contrast to anemias resulting from early stage defects, this group of disorders are resistant to erythropoietin (EPO) therapy since late-stage erythroblast differentiation and maturation is EPO independent. Transfusion, often associated with iron overload and alloimmunization, remains the principal approach to care. Fortunately, however, several molecular determinants of dyserythropoiesis have been recently identified. It is possible that these discoveries may reveal common pathways leading to dyserythropoiesis. This workshop will consider the gaps in our knowledge and technology that are barriers to our understanding of the underlying biologies that may lead to effective new treatments for late stage erythroid maturation defects. This workshop will also provide an opportunity for the research community to cooperatively consider the essential next steps for the field.
September 26, 2016 to September 27, 2016
This workshop has two main objectives: (a) to assess recent developments in statistical methods relevant to NHLBI studies; (b) to identify the major challenges and important issues related to these statistical and analytical methods.