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NHLBI in the Press
The majority of nutritional supplements or diets are not linked to longer life or protection against heart disease, according to an analysis of 277 clinical trials using 24 different interventions and totaling 992,129 participants.
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NHLBI in the Press
Researchers found that the majority of study participants with variations in the DNA sequence for the titin gene did not predict signs of cardiac decline or idiopathic dilated cardiomyopathy (DCM)—a potentially life-threatening condition due to enlarged, weakened ventricles that has no known cause.
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NHLBI in the Press
Researchers funded by NHLBI have provided evidence to support a simple measurement for diagnosing clinically significant airflow obstruction, the key characteristic of chronic obstructive pulmonary disease (COPD), the fourth leading cause of death in the United States.
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NHLBI in the Press
The improvement in cholesterol levels among children and teens in the United States still leaves a half empty glass. There have been hopeful changes, but still 50% of Americans ages 6 to 19 have less than ideal cholesterol levels; and as many as 25% of them are in the clinically high range.
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NHLBI in the Press
Researchers used specially-designed 3D printing technology to develop an artificial air sac that structurally and functionally mimics similar structures found in the human lung, including the ability to pulsate or “breathe” without bursting. The development represents a step toward the much anticip
Dr. Clare Waterman at her lab
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NHLBI in the Press
Clare M. Waterman, Ph.D., NIH distinguished investigator and director of the NHLBI Laboratory of Cell and Tissue Morphodynamics has been elected to the National Academy of Sciences (NAS), the highest honor for American scholars in recognition of their distinguished and continuing achievements in ori
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NHLBI in the Press
Despite new technologies existing to discover novel disease biomarkers, many molecular platforms are resource intensive and require rigorous sample collection.
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NHLBI in the Press
In a new study that links sleep insufficiency to heart disease, researchers are reporting that people who sleep fewer than 7 hours per night have lower levels of certain gene-regulating molecules called microRNAs, which play a role in reducing inflammation and support blood vessel health.
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NHLBI in the Press
Researchers funded by NHLBI found that adults with sickle cell disease have worse performance in several cognitive tests than their healthy siblings. The disadvantage remained the same even for the patients treated with hydroxyurea.
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NHLBI in the Press
NHLBI-funded researchers have developed a model of the human respiratory airways that, by mimicking its behaviors, revealed the mechanism of asthmatic bronchial spasms.
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NHLBI in the Press
An NHLBI-funded study found that the higher the consumption of dietary cholesterol or eggs, the higher the incidence of cardiovascular disease, which includes heart disease and stroke, and death from any cause among U.S. adults.
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NHLBI in the Press
Compared to drug therapies, catheter ablation, a common cardiovascular procedure, didn’t achieve a significant reduction of strokes, deaths, and other complications in patients with atrial fibrillation.
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NHLBI in the Press
A clinical trial partly funded by NHLBI found that integrating behavioral therapy for weight loss and antidepressant medications as needed for patients with co-occurring obesity and depression had a positive effect for both conditions.
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NHLBI in the Press
An increasing number of studies have linked psoriasis, a chronic inflammatory skin disease, to the development of heart disease. Now, a new study provides further evidence for this link by demonstrating how certain blood cells might interact in a way that damages blood vessels in people with this ps
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NHLBI in the Press
Think sleeping in on the weekend can repair the damage for a week of sleepless nights? Think again. Researchers are reporting that weekend ‘catch-up’ sleep might make things worse, including an increased risk of weight gain.  
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NHLBI in the Press
A large NHLBI-funded prospective study of sedentary time and cardiovascular disease in women found that each additional hour/day spent not sitting was associated with a 12 percent lower risk of any cardiovascular disease and a 26 percent lower risk of heart disease in women who were 63-97 years old.
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NHLBI in the Press
Research has shown that cancer cells produce PD-L1 to evade attack from the immune system. Now there is evidence that a similar mechanism may occur in idiopathic pulmonary fibrosis (IPF), a chronic, progressive lung disease that causes buildup of scar tissue in the lungs and prevents oxygen transpor
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NHLBI in the Press
Being a morning person is a behavioral indicator of a person’s underlying circadian rhythm. Using genome-wide data from 697,828 UK Biobank and 23andMe participants, researchers recently increased the number of genetic loci associated with being a morning person from 24 to 351.
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NHLBI in the Press
The incidence of obesity has reached alarming proportions worldwide, and increasing evidence suggests that the parents’ nutritional status may predispose their offspring to lipotoxic heart disease—the accumulation of fat in heart cells.
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NHLBI in the Press
In a study partly funded by NHLBI, a team of researchers found a 25 percent reduction in the risk of cardiovascular disease among participants who consumed a Mediterranean-type diet rich in plants and olive oil and low in meats and sweets.
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NHLBI in the Press
A new NHLBI-funded study showed that a change in the type of breathing tube paramedics use to resuscitate patients with sudden cardiac arrest can significantly improve the odds of survival and save thousands of lives. More than 90 percent of Americans who experience sudden cardiac arrest die before,
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NHLBI in the Press
There might be a way to get the blood pressure lowering benefits of exercise in pill form, a new study in animals suggests. Researchers showed that by increasing the body's supply of beta hydroxybutyrate, a chemical produced predominantly by the liver, it is possible to regulate high blood pressure
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NHLBI in the Press
Researchers funded by NHLBI have performed prenatal gene editing to prevent a lethal congenital metabolic disease in mice. The study findings, published in Nature Medicine, offer proof of concept for the possibility of genetic therapies before birth.
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NHLBI in the Press
Silent heart attacks—also known as unrecognized myocardial infarctions (MI)—that show up only on magnetic resonance imaging (MRI) are associated with an increased risk of death over the long term compared with recognized MI, researchers are reporting.
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NHLBI in the Press
The mammalian liver possesses the remarkable ability to regenerate after injury, potentially restoring up to 70% of its lost mass and function in just a few weeks.
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NHLBI in the Press
Tuberculosis is a significant global health threat, with one-third of the world’s population infected with its causative agent Mycobacterium tuberculosis (Mtb).
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NHLBI in the Press
The population of the Mediterranean island of Sardinia has made important contributions to genome-wide association studies of complex disease traits.
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NHLBI in the Press
A protein called sarcolipin protects mice against obesity, according to a recent study. Additional experiments showed that this protein regulates energy metabolism in muscle.
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NHLBI in the Press
Researchers partly funded by NHLBI have identified a drug that could treat, and perhaps reverse, pulmonary arterial hypertension, a severe lung disease with a five-year survival rate of 50 percent. The findings were published in the American Journal of Respiratory Critical Care Medicine.