Sickle Cell Disease - Risk Factors - Risk Factors

In the United States, most people who have sickle cell disease are of African ancestry or identify themselves as Black.

  • About 1 in 13 Black or African American babies is born with sickle cell trait.
  • About 1 in every 365 Black or African American babies is born with sickle cell disease.

There are also many people who have sickle cell disease who come from Hispanic, southern European, Middle Eastern, or Asian Indian backgrounds.

About 100,000 Americans have sickle cell disease.