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NHLBI Obesity Research

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The Multi-Ethnic Study of Atherosclerosis (MESA)

Project Period: 1/15/1999–8/14/2015
Contact: Dr. Jean Olson

The Multi-Ethnic Study of Atherosclerosis (MESA) http://mesa-nhlbi.org/external disclaimer is a study that investigate the prevalence, correlates, and progression of subclinical CVD and risk factors that predict progression to clinically overt CVD, and that predict progression of subclinical disease itself, in a population-based sample of 6,800 ethnically diverse men and women. The cohort was recruited from six Field Centers and characterized with respect to coronary calcification using computed tomography, ventricular mass and function using magnetic resonance imaging, and other measures at baseline. Several subclinical disease measures were repeated in 3 subsequent examinations. Participants will be followed for identification and characterization of incident CVD events and interventions received. The study is planning for renewal, including an Exam 5 that will include a repeat cardiac MRI, including myocardial tagging to measure ventricular function. Approximately half of the cohort are planned to undergo repeat cardiac CT and carotid ultrasound, supported by the EPA-funded ancillary study MESA Air Pollution.

Last Updated July 2014


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