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NHLBI Obesity Research

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The Jackson Heart Study (JHS)

Project Period: 10/15/1997–10/31/2018
Contact: Ms. Cheryl Nelson

JHS Websiteexternal disclaimer

Highlights of JHS New Findings for 2015-2016 pdf file icon (PDF, 106 KB)

Selected 2014 Publicationspdf file icon (PDF, 104 KB)

The Jackson Heart Study Data Book: A Report to the Cohort and Community pdf file icon (PDF, 4.06 MB)

The Jackson Heart Study Data Book: A Report to the Cohort and Community, Accessible Web Version

The Jackson Heart Study (JHS) study is the largest investigation of causes of CVD in an African-American population, involving 5,306 men and women in Jackson, MS. It is uniquely positioned to investigate CVD risk factors, especially manifestations related to hypertension such as coronary artery disease, heart failure, stroke, peripheral arterial disease, and renal disease.

Enrolled JHS participants received three back-to-back examinations that produced extensive longitudinal data on traditional and putative CVD risk factors, socioeconomic and sociocultural factors, biochemical analytes; and measures of subclinical disease. Baseline Exam 1 (2000-2004) included demographics, psychosocial inventories, medical history, anthropometry, resting and ambulatory blood pressure, phlebotomy and 24-hour urine collection, ECG, echocardiography, and pulmonary function. Exam 2 (2005-2008) included some repeated measures from Exam 1 and several new components, including distribution of self-monitoring blood pressure devices, DNA collection, and CT scans of the heart, aorta, and abdomen. Exam 3 (2009-2013) contained repeat measures from the first two exams and new questionnaires to assess sleep history and cognitive function and cardiac MRI scans with gadolinium MRI contrast in a subset of participants to identify silent myocardial infarctions. Individualized reports are provided to each participant and, with consent, to their health care providers, that include clinically relevant results and indications of any abnormalities of clinical significance. Since the baseline exam, cohort members have been contacted every 12 months to obtain information on vital status, current residence, major illness or injury, and hospitalizations occurring between contacts to identify incident clinical CVD events of interest.

The institutions involved in the JHS contract are the University of Mississippi Medical Center (Data Acquisition Center and Data Coordinating Center) and two Historically Black Colleges and Universities, Jackson State University (Community Outreach Center and Graduate Training and Education Center) and Tougaloo College (Undergraduate Training and Education Center). Students from the Training and Education Centers are given the opportunity to take course work in public health and epidemiology and gain practical experience in health research to help prepare them for potential careers in biomedical research and professions.

Last Updated September 2017


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