Clinical Trials

Do you or your child have overweight or obesity? This study aims to find effective ways to prevent and treat obesity and metabolic syndrome in African American communities. The study will test the effectiveness of a family-based comprehensive health and fitness programs involving community health workers. Participants must be 12 years old or older and African American and have overweight or obesity. This study takes place in Charleston, South Carolina.

Do you or your child have Williams Syndrome (WS) or supravalvular aortic stenosis (SVAS) or are you interested in helping research on these conditions? The blood vessels in people with WS or SVAS have less elasticity, which can cause them to narrow. This study aims to see how blood vessel differences in people with these conditions affect organs in the body including the heart, gut, kidneys, and brain. This study is open to people with one of these conditions or healthy volunteers between 3 and 85 years old. The study takes place at the NIH Clinical Center in Bethesda,

Does your child have overweight or obesity? This study is testing whether a treatment program called FIT Families can help treat obesity in African American teenagers. FIT Families is a 6-month family-based program that involves home visits by community health workers. Participants in this study must be 12 to 17 years old, African American, and diagnosed with obesity. This study is located in South Carolina.

Are you an adult with sickle cell disease who’s recently had a vaso-occlusive episode? This study investigates better ways for emergency departments (EDs) to manage vaso-occlusive episodes, or pain crises, in people with sickle cell disease. This study is incorporating “Individualized Pain Plans” into patients’ electronic health records to allow for faster and more accurate treatment in the ED. To participate in this study, you must be between the ages of 18 and 45 and have sickle cell disease. You must also have had at least one visit to a participating ED in the past 90 days due to pain from a vaso-occlusive episode and at least one visit at the study site sickle cell disease clinic within the past 12 months. This study takes place in multiple locations in the United States.