Find NHLBI Clinical Trials

Search selected NHLBI-supported clinical trials and observational studies by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.

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Showing 1 - 10 out of 44 results
Recruiting
Have you had a heart attack, and do you want to help improve strategies for blood transfusion? The study is comparing two strategies for blood transfusions in heart attack patients who have anemia—whether to give a blood transfusion when the hemoglobin level is less than 10 g/dL, or to give blood only when the blood count is below 8 g/dL. To participate in this study, you must be at least 18 years old, have anemia, and be hospitalized for a heart attack. The study is located in New Brunswick, New Jersey.
Adult, Older Adult
Recruiting
Were you or your child recently diagnosed with VTE? This study is testing a six-week course of blood-thinning medicines for the treatment of venous thromboembolisms (VTE) to see if they are as effective as the standard treatment course of three months. To participate in this study, you or your child must be younger than 21 years old. This study has 54 locations in Alabama, Arizona, California, Connecticut, Florida, Georgia, Illinois, Indiana, Kentucky, Maryland, Massachusetts, Michigan, Missouri, New Jersey, New York, North Carolina, Ohio, Oklahoma, Oregon, Pennsylvania, South Carolina, Texas, Utah, Virginia, Wisconsin, Australia, Austria, Canada, Israel, and the Netherlands.
Child, Adult
Recruiting
Do you or your child have sickle cell disease and also have an interest in contributing to long-term data collection? This study is monitoring patients and collecting biological samples from patients who have sickle cell disease to better understand long-term outcomes. Participants can be any age and must have sickle cell disease. This study is located in six sites in Illinois, Louisiana, North Carolina, and Tennessee.
All Ages
Recruiting
Are you scheduled for a stem cell transplant with cord blood? This study will assess the safety and effectiveness of certain cord blood transplants. The study will help researchers learn the best methods for collecting, storing, and using cord blood in transplants. To participate in this study, you must have a disorder that compromises your body’s ability to make blood cells. This study is located in Bethesda, Maryland.
All Ages
Recruiting
Illinois
Are you an adult with a diagnosed sleep phase disorder? This study aims to assess the sleep patterns and quality of sleep in people who have sleep phase disorders to determine how the disorders affect their circadian rhythms. To participate in this study, you must be at least 18 years old and have a sleep phase disorder, such as advanced sleep-wake phase syndrome or delayed sleep-wake phase syndrome. This study is located in Chicago, Illinois.
Adult, Older Adult
Recruiting
Are you between 40 and 85 with worsening idiopathic pulmonary fibrosis? This study aims to test a new combination treatment for acute exacerbations, a life-threatening complication of idiopathic pulmonary fibrosis (IPF) that has no approved treatment. The treatment is meant to help stop part of the immune system from further injuring the lung tissue. To participate in this study, you must be between 40 and 85 years old and have worsening IPF. This study is located in Birmingham, Alabama; Boston, Massachusetts; Philadelphia, Pennsylvania; and Pittsburgh, Pennsylvania.
Adult, Older Adult
Recruiting
Illinois
Is your premature newborn in a neonatal intensive care unit in Chicago, Illinois? This study is investigating how brain development affects breathing in premature newborns. To participate in this study, your newborn must have been born prematurely between 24 and 29 weeks’ gestation and admitted to the neonatal intensive care unit within a week of birth. This study is located in Chicago, Illinois.
Child
Recruiting
Are you an adult woman who would like to help develop methods to prevent the worsening of LAM? This study aims to discover whether earlier and longer treatment with a lower dose of sirolimus can help prevent LAM from getting worse over time. To participate in this study, you must be female, be at least 18 years old, and have been diagnosed with LAM. This study is located in Atlanta, Georgia; Boston, Massachusetts; Chicago, Illinois; Cincinnati, Ohio; Denver, Colorado; Nashville, Tennessee; Palo Alto, California; Philadelphia, Pennsylvania; and Seattle, Washington.
Adult, Older Adult
Female
Recruiting
Illinois
Are you an adult interested in comparing effects of different exercise training on blood pressure? This study aims to compare how different types of exercise can affect blood pressure in African Americans. Participants will do either aerobic activities, focusing on raising their heart rate, or muscle-strengthening resistance activities, focusing on weights, for 24 to 26 weeks. To participate in this study, you must be between 18 and 50 years old, have a sedentary lifestyle and elevated blood pressure, and have been born in the United States to either two African American or two non-Hispanic Caucasian parents. This study is located in Chicago, Illinois.
Adult
Recruiting
Illinois
Do you want to take part in a supervised exercise program and help science? This study will see how aerobic and resistance exercise affect blood pressure. In the study you will take part in one of these exercise programs for two months. You will be supervised by a physical therapist or an exercise physiologist during the exercises. To participate in this study, you must be between 18 and 55 years old, and not be taking medicine for high blood pressure. This study is located in Chicago, Illinois.
Adult