Find NHLBI Clinical Trials

Search selected NHLBI-supported clinical trials and observational studies by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.

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Showing 1 - 10 out of 30 results
Recruiting
Florida
Are you an adult whose high blood pressure does not improve with lifestyle changes and medicines? This study will assess whether minocycline, an antibiotic with anti-inflammatory effects, can improve blood pressure control in patients who do not respond to medicines in combination with lifestyle changes, such as physical activity, weight loss, and healthy eating patterns. To participate you must be at least 18 years old and have high blood pressure that does not respond to treatment with three different high blood pressure medicines even when used at the maximum doses. Please note that this study is in Gainesville, Florida.
Adult, Older Adult
Recruiting
Maryland
Are you an African American living in Washington, D.C., or Montgomery or Prince Georges counties in Maryland? This study will examine how your genes and health behaviors and where you live and work contribute to your risk of heart disease. To participate you must be between 21 and 65 years old. This study is located in Bethesda, Maryland.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
Indiana
Have you been diagnosed with high blood pressure while pregnant? This study is investigating whether a mother’s blood pressure during pregnancy affects her newborn’s lung development. To participate in this study, your newborn must have been born either prematurely at more than 25 weeks’ gestation or at full term to a healthy mother or a mother who was diagnosed with high blood pressure during pregnancy. This study is located in Indianapolis, Indiana.
All Ages
Recruiting
Minnesota
Are you a healthy adult who regularly sleeps for 6.5 or fewer hours? This study is examining whether getting enough sleep can lower your risk of high blood pressure. To participate in this study, you must be between 18 and 65 years old, regularly sleep for 6.5 or fewer hours, and be able to adjust your sleep schedule for the study. This study is located in Rochester, Minnesota.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
New York
Are you an adult who does not have high blood pressure? Circadian rhythms control daytime and nighttime changes in blood pressure. This study is examining the links between stress, loss of sodium through urine, and circadian rhythms in controlling blood pressure. To participate in this study, you must be at least 21 years old and not have high blood pressure. This study is located in New York, New York.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
Minnesota
Are you an adult who has uncontrolled high blood pressure? This study will see whether an early notification system for health professionals can help manage patients’ high blood pressure, especially among those who have had a stroke or have an increased risk of stroke. To participate in this study, you must be between 18 and 85 years old and have high blood pressure that is not controlled by medicine and lifestyle changes. This study is enrolling native English, Spanish, or Hmong speakers. The study is located in Minneapolis, Minnesota.
Adult, Older Adult
Recruiting
Louisiana
Mississippi
Do you have high blood pressure, and do you receive care at a community-based clinic in the South? This study will explore an intensive high blood pressure management approach at participating community-based clinics. The approach aims to lower participants’ systolic blood pressure to 120 mm Hg. To participate in this study, you must be at least 40 years old, understand English, and not be pregnant. The study is located in Louisiana, Alabama, and Mississippi.
Adult, Older Adult
Recruiting
Iowa
Do you live in Iowa and want to work with a pharmacist to manage your high blood pressure? This study will test a program that uses pharmacists to help people manage high blood pressure. You will be given a blood pressure monitor to take readings at home and text them to a pharmacist. You will then either talk to the pharmacist once or be part of the more intensive program where the pharmacist develops a care plan and monitors you for a year. To participate in this study, you must be older than 21, have had a systolic pressure greater than 145 mm Hg or diastolic pressure greater than 95 mm Hg at your previous clinic visit, and be a patient at the Family Medicine, River Crossings, Scott Blvd, or Muscatine University of Iowa Clinics. This study is located in Iowa.
Adult, Older Adult
Recruiting
Florida
Do you want to help researchers understand the link between gut bacteria and high blood pressure? This study aims to explore the relationship between gut microbiota (tiny organisms that live in the digestive system) and high blood pressure. The researchers will compare gut microbiota in participants with normal blood pressure, controlled high blood pressure, uncontrolled high blood pressure, and high blood pressure that is resistant to treatment. To participate in this study, you must be between 18 and 80 years old and not be pregnant or taking an antibiotic. This study is located in Gainesville, Florida.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
New York
Do you want to get better at taking your blood pressure medicine? This study will test a program aimed at helping motivate people to take their blood pressure medicine. Each day, participants who took their medicine will be eligible to win a prize through a smartphone app that tracks whether they are taking their medicine. To participate in this study, you must be at least 18 years old and have an active prescription for high blood pressure medication. This study is located in New York, New York.
Adult, Older Adult