Clinical Trials

Are you 75 years old or older and interested in participating in a clinical trial where researchers are studying whether statins, which are often used to treat high cholesterol, can help improve heart and brain health. To participate, you cannot have cardiovascular disease or dementia. The study is taking place at locations in Alabama, Arizona, Arkansas, California, Connecticut, Florida, Georgia, Illinois, Indiana, Iowa, Kansas, Kentucky, Louisiana, Maine, Maryland, Massachusetts, Michigan, Minnesota, Mississippi, Missouri, Nebraska, Nevada, New York, North Carolina, Ohio, Pennsylvania, Rhode Island, South Carolina, Tennessee, Texas, Utah, Virginia, West Virginia, Wisconsin, and Puerto Rico.

Have you had a baby within the past month? If so, you may be able to participate in this clinical trial where researchers are testing out a home visitation program for women who have recently given birth. Participants in the study will be visited by trained nurses who will help with soothing, feeding, sleep, and physical activity. To participate, you must be at least 18 years old and have reliable access to the internet. Mother and infant must also be enrolled in the Nurse Family Partnership program. This study is taking place in Altoona and Danville, Pennsylvania.

Are you interested in participating in a clinical trial on heart health? In this trial, researchers are testing ways to help lower blood pressure and reduce cardiovascular disease as people age. To participate, you must be 65 to 80 years old, and you must not have high blood pressure or take medication for high blood pressure. The study is taking place in Hershey, Pennsylvania.

Do you have endometriosis? Researchers in this clinical trial are studying the effect of therapy that lowers estrogen levels on the risk of cardiovascular disease among women with endometriosis. To join the study, you must be between the ages of 18 and 45. The study is enrolling women with endometriosis, as well as women without endometriosis. The study is taking place in New Haven, Connecticut.

Do you have mitral valve disease? This clinical trial is testing different types of images taken of the heart to learn more about mitral valve disease and the best ways to treat it. You must be 60 years old to participate. The study is enrolling patients in locations in Arkansas, California, Georgia, Indiana, Louisiana, Maine, Maryland, Massachusetts, Michigan, Missouri, New York, North Carolina, Ohio, Pennsylvania, and Quebec City, Canada.

Are you at least 18 years old and have heart failure? Researchers in this clinical trial are testing whether a new type of hormone therapy may help with symptoms and quality of life for people who have heart failure. Participants will take medication by mouth daily. The study is taking place in Philadelphia, Pennsylvania.

Do you have heart failure that is well controlled through medication and attending regular appointments with your healthcare provider? This clinical trial is testing a dietary supplement taken by mouth twice a day for five days to see if it can help patients with heart failure. You must be at least 18 years old to participate. The study is taking place in New Haven, Connecticut.

Do you have heart failure? In this clinical trial, researchers are using images of the heart and blood tests to learn more about Black and Hispanic patients with heart failure. You may be able to participate if you are at least 60 years old; of Black, Hispanic, or Caribbean origin; and have been diagnosed with heart failure. The study is taking place in locations in Connecticut, Massachusetts, and New York.

Do you want to help find new treatments for heart failure with preserved ejection fraction? This study is testing whether a medicine called spironolactone can help treat heart failure with preserved ejection fraction when paired with the standard treatment. Spironolactone helps to remove excess water and sodium from the body. To participate in this study, you must be between 50 and 99 years old and diagnosed with heart failure with preserved ejection fraction.

Do you have heart failure with reduced ejection fraction and thyroid problems? This study will test whether hormone therapy with liothyronine is safe and effective for treating people who have heart failure with reduced ejection fraction and low triiothyronine (T3) syndrome. Low T3 syndrome is a type of thyroid hormone that helps control many functions of your body. To participate in this study, you must be at least 18 years old and diagnosed with heart failure with reduced ejection fraction. This study is located in Philadelphia, Pennsylvania.