Find NHLBI Clinical Trials
Search selected NHLBI-supported and by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.
Location
Age Group
Showing 1 - 10 out of 10 results
Recruiting
New York
Pennsylvania
22q11.2 deletion syndrome is a genetic disorder that can cause heart defects, facial abnormalities, and developmental and learning disabilities. The severity of the disorder can vary widely among people. This study will analyze DNA from people with 22q11.2 deletion syndrome to identify genetic variations that may affect the severity of the disorder.
All Ages
Recruiting
Does your child have Down Syndrome? Did they have a complete atrioventricular septal defect (CAVSD) repair within the first year of their life? Researchers in this study are investigating how the
brain develops in children with Down Syndrome who have congenital heart disease. To participate, your child must be between 5 and 12 years old and have Down Syndrome. The study will enroll children who have congenital heart disease as well as children who do not have congenital heart disease. The study is taking place in locations in Delaware, Georgia, Indiana, Massachusetts, Michigan, Missouri, New York, Ohio, Pennsylvania, South Carolina, Texas, Utah, Washington, D.C., and Toronto, Canada
brain develops in children with Down Syndrome who have congenital heart disease. To participate, your child must be between 5 and 12 years old and have Down Syndrome. The study will enroll children who have congenital heart disease as well as children who do not have congenital heart disease. The study is taking place in locations in Delaware, Georgia, Indiana, Massachusetts, Michigan, Missouri, New York, Ohio, Pennsylvania, South Carolina, Texas, Utah, Washington, D.C., and Toronto, Canada
Child
Accepting Healthy Volunteers
Recruiting
Do you or one of your children have a congenital heart defect?
This study will find both common genetic causes of congenital heart disease and ways that genes influence results of medical treatment. To participate in this study, you or your child must have congenital heart disease. This study is located in Los Angeles, Palo Alto, and San Francisco, California; New Haven, Connecticut; Boston, Massachusetts; New York and Rochester, New York; Philadelphia, Pennsylvania; and Salt Lake City, Utah.
All Ages
Recruiting
Pennsylvania
Do you have high blood pressure, high A1C levels, or have overweight or obesity? Researchers are testing if a program helps increase physical activity for people at risk of cardiovascular disease. Participants will receive remote coaching and wear a physical activity tracker. To join, you must be 40 to 70 years old and can access the internet. The study is taking place in Pittsburgh, Pennsylvania.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
North Carolina
Do you have overweight or obesity? Researchers are testing whether messages sent through a mobile app can help people lose weight. To participate, you must be 18 to 39 years and own a smartphone with a data and text messaging plan. The study is taking place in Chapel Hill, North Carolina.
Adult
Recruiting
Pennsylvania
Is your child black and 8 to 11 years old?
This study is testing a way of enhancing sleep in children with the goal of preventing obesity. To participate in this study, your child must be 8 to 11 years old and must be black or African American. This study is located in Philadelphia, Pennsylvania.
Child
Accepting Healthy Volunteers
Recruiting
Pennsylvania
Rhode Island
Does your child have overweight or obesity? This study is exploring the link between obesity and sleep deprivation in children. Researchers will test whether participants who do not get enough good quality sleep have trouble making healthy food choices. Participants in this study must be 8 to 12 years old and have overweight or obesity. This study takes place in Pittsburgh, Pennsylvania; and Providence, Rhode Island.
Child
Accepting Healthy Volunteers
Recruiting
North Carolina
Are you an adult with both asthma and obesity? This study is testing whether a medicine called L-citrulline can help treat asthma and improve lung function in people who have obesity. To participate in this study, you must be 18 to 65 years old and have asthma and obesity. This study takes place in Durham, North Carolina.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
Are you an adult who has overweight or obesity and would be interested in a weight-loss study? This study is testing whether a medicine called phentermine is safe and effective for treating obesity over a long period. This study has multiple locations in the United States.
Adult, Older Adult
Recruiting
Pennsylvania
Rhode Island
Does your child have overweight or obesity or just want to be in a study on sleep and eating habits? Overweight and obesity are common in children who do not get enough good quality sleep. This study aims to understand how sleep deficiency can affect a child’s ability to make good food choices. Researchers will ask participants to spend either 8 or 11 hours in bed and to keep track of their food choices. Participants in this study must be 8 to 12 years old. This study takes place in Pittsburgh, Pennsylvania and Providence, Rhode Island.
Child
Accepting Healthy Volunteers