Clinical Trials

Are you an adult with congenital heart disease? If so, you may be able to participate in a clinical trial where researchers are testing a program for stress management for people with congenital heart disease. Participants must be 18 years old and have complex congenital heart disease. To participate, you must also receive care in the University of Washington health system. The study is
taking place in Seattle, Washington.

Does your child have Down Syndrome? Did they have a complete atrioventricular septal defect (CAVSD) repair within the first year of their life? Researchers in this study are investigating how the
brain develops in children with Down Syndrome who have congenital heart disease. To participate, your child must be between 5 and 12 years old and have Down Syndrome. The study will enroll children who have congenital heart disease as well as children who do not have congenital heart disease. The study is taking place in locations in Delaware, Georgia, Indiana, Massachusetts, Michigan, Missouri, New York, Ohio, Pennsylvania, South Carolina, Texas, Utah, Washington, D.C., and Toronto, Canada

Do you or one of your children have a congenital heart defect? This study will find both common genetic causes of congenital heart disease and ways that genes influence results of medical treatment. To participate in this study, you or your child must have congenital heart disease. This study is located in Los Angeles, Palo Alto, and San Francisco, California; New Haven, Connecticut; Boston, Massachusetts; New York and Rochester, New York; Philadelphia, Pennsylvania; and Salt Lake City, Utah.

Are you a greater Boston resident aged 24 to 30? This study aims to bridge the gap in knowledge between known executive function deficits in childhood congenital heart disease and adult well-being. The study is Recruitinghealthy volunteers. To participate in this study, you must be between the ages of 24 and 30, live in the greater Boston area, read fluently in English, and not have metal implants, a pacemaker, or orthodontia that would prevent MRI. This study is located in Boston, Massachusetts.

Do you have heart failure and live near Massachusetts General Hospital in Boston, Massachusetts? Researchers are testing whether an online program helps lower the number of times patients with heart failure return to the hospital. You may be able to participate if you are at least 18 years old, have heart failure, and live within 30 miles of Massachusetts General Hospital in Boston.

Are you an adult planning to get a left ventricular assist device (LVAD) implant to treat heart failure? If so, you may be able to take part in a clinical trial about heart failure. Researchers are testing whether a dietary supplement can improve heart function for people with advanced heart failure. To participate, you must be at least 18 years old and be scheduled for elective LVAD implantation. The study is taking place in Seattle, Washington.

Do you have heart failure? In this clinical trial, researchers are using images of the heart and blood tests to learn more about Black and Hispanic patients with heart failure. You may be able to participate if you are at least 60 years old; of Black, Hispanic, or Caribbean origin; and have been diagnosed with heart failure. The study is taking place in locations in Connecticut, Massachusetts, and New York.

Are you an adult with heart failure? Unplanned weight loss is quite common among people with heart failure. Researchers in this clinical trial are studying whether adding a protein supplement to daily meals can help prevent muscle and weight loss for people with heart failure. To participate, you must be at least 18 years old and have heart failure. The study is taking place in Boston, Massachusetts.

Are you an adult with heart failure? A clinical trial is testing if a supplement drink helps people with heart failure. Participants will visit the study site once where they will be served a light breakfast with the study’s supplement drink. Researchers will perform a physical exam and draw blood several times during the visit. The study is taking place in Durham, North Carolina.

Do you want to help find new treatments for heart failure with preserved ejection fraction? This study is testing whether a medicine called spironolactone can help treat heart failure with preserved ejection fraction when paired with the standard treatment. Spironolactone helps to remove excess water and sodium from the body. To participate in this study, you must be between 50 and 99 years old and diagnosed with heart failure with preserved ejection fraction.