Clinical Trials

Does your child have obesity? In this study, children and teens, 7 to 13 years of age with obesity and their parents will learn about nutrition, behavior changes, and exercise through the Bright Bodies lifestyle program. Researchers want to see if this program can help lower weight gain and screen time, improve sleep, eating behaviors, and quality of life, and reduce parental stress. The study is taking place at locations in Alabama, California, and Maine.

The purpose of this study is to see if adding a drug called Regadenoson to the EVLP circulation reservoir during perfusion of marginal donor lungs will help increase the likelihood that the donor lungs will become usable for transplantation.

Do you have short telomeres and a telomere gene mutation? Some people who have aplastic anemia have very short telomeres, which protect the ends of DNA in chromosomes. This study is testing whether low doses of the medicine danazol help prevent telomeres from getting shorter and reduce signs of damage from aplastic anemia or related conditions. Participants in this study must be 3 years or older and have a telomere disease and signs of aplastic anemia, lung disease such as pulmonary fibrosis, or liver disease. This study is located in Bethesda, Maryland.