Clinical Trials

Do you have COPD? Researchers in this study are studying the benefit of a wellness program for people with COPD. You may be able to participate if you are at least 40 years old, diagnosed with COPD, and able to perform exercises with your lower body. The study is taking place in San Francisco, California.

Do you have asthma, COPD, or asthma COPD overlap syndrome? This study will look at whether a health coach can help people who have asthma, COPD, or asthma-COPD overlap syndrome with their condition. You will be randomly selected to meet with either a lung specialist alone or a lung specialist and a health coach, who will give you recommendations to improve your care and better manage your condition. To participate in this study, you must be age 18 or older, have asthma or COPD, and not already be seeing a lung specialist. You also must get your care from one of 10 health centers in San Francisco, California. This study is located in San Francisco, California.

Do you have heart failure that is well controlled through medication and attending regular appointments with your healthcare provider? This clinical trial is testing a dietary supplement taken by mouth twice a day for five days to see if it can help patients with heart failure. You must be at least 18 years old to participate. The study is taking place in New Haven, Connecticut.

Do you have heart failure? In this clinical trial, researchers are using images of the heart and blood tests to learn more about Black and Hispanic patients with heart failure. You may be able to participate if you are at least 60 years old; of Black, Hispanic, or Caribbean origin; and have been diagnosed with heart failure. The study is taking place in locations in Connecticut, Massachusetts, and New York.

Has your child received a Fontan palliation operation? If so, they may be able to join a clinical trial that is testing whether exercise can help patients who have had this procedure. Your child must be between 8 and 19 years old, had a Fontan palliation, and can exercise. A study team member will observe the participants doing aerobic and resistance exercises live on video. The study is taking place in Palo Alto, California.

Are you an adult with heart failure and an implanted CardioMEMS pulmonary artery pressure (PAP) monitor? This study is investigating whether psychological stress can make the symptoms of heart failure worse. Participants of this study will have their blood pressure monitored and their blood drawn after undergoing mental stress in a controlled setting, within a laboratory. To participate in this study, you must be at least 18 years old. This study takes place in New Haven, Connecticut.

Do you have heart failure and need treatment with intravenous (IV) diuretics? This study is exploring the use of chloride supplementation in people with heart failure who require treatment with IV diuretics, which are used to help rid your body of excess water and salt. To participate in this study, you must have heart failure with signs of volume overload (rales, edema, elevated jugular venous pressure [JVP], or weight gain of at least 5 pounds) requiring treatment with IV diuretics. This study takes place in New Haven, Connecticut.