Find NHLBI Clinical Trials
Search selected NHLBI-supported and by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.
Location
Age Group
Showing 1 - 10 out of 40 results
Recruiting
Do you have symptoms of a lung disease (such as long-term wet cough, bronchiectasis, or recurrent pneumonia) with no genetic diagnosis? This study aims to develop new ways to diagnose primary ciliary dyskinesia (PCD) or primary immune deficiency (PID), two conditions that can have similar symptoms. Researchers will combine information from genetic testing, lung imaging, and lung function tests to diagnose and tell the difference between these two conditions. Participants in this study must be 5 to 45 years old and must have symptoms of a serious lung disease but no diagnosis. This study is taking place at multiple locations in the United States and in Canada, including the NIH Clinical Center in Bethesda, Maryland.
Child, Adult
Recruiting
Are you an adult with a non-tuberculous mycobacteria (NTM) infection? This study is testing the effectiveness of a medicine called clofazimine (Lamprene) to treat NTM. To participate in this study, you must be an adult with a NTM infection. This study is located at the NIH Clinical Center in Bethesda, Maryland.
Recruiting
Maryland
Do you have bronchiectasis and get frequent lung infections? This study is exploring what causes frequent lung infections in people with bronchiectasis. Researchers will look at whether changes to a person's genes or immune system can raise the risk of these frequent infections. Participants in this study must be at least 5 years old and either healthy, diagnosed with bronchiectasis, or have a history of frequent lung infections. This study is located at the NIH Clinical Center in Bethesda, Maryland.
All Ages
Accepting Healthy Volunteers
Recruiting
Maryland
Are you a healthy adult or someone with a history of lung infections such as pneumonia or bronchitis? This study aims to compare fluid and tissue samples from the nose and lungs of healthy adults with people who have a lung disease. Researchers hope to learn why some people are more susceptible to certain infections. This study is located at the NIH Clinical Center in Bethesda, Maryland.
All Ages
Accepting Healthy Volunteers
Recruiting
North Carolina
Do you or your child have PCD and want to help researchers better understand how cilia are formed? This study aims to identify the genes that control how cilia are formed. Cilia are hairlike structures that line the airways and protects the normal lung. The study will also identify how mutations to these genes can cause PCD. This study takes place in Chapel Hill, North Carolina.
All Ages
Accepting Healthy Volunteers
Recruiting
Missouri
North Carolina
Do you or your child have primary ciliary dyskinesia (PCD) or primary immune deficiency (PID)? This study aims to identify genes that cause these two conditions, which can have similar symptoms. The results from this study will help researchers find new ways to treat breathing and hearing problems caused by these two conditions in a cross-sectional cohort of patients with PCD and PID. Participants in this study must be 5 to 45 years old. This study is taking place at multiple locations in the United States and in Canada.
Child, Adult
Recruiting
Do you or your child have symptoms of a serious lung disease but no diagnosis? This study aims to develop new ways to diagnose primary ciliary dyskinesia (PCD) and primary immune deficiency (PID), two conditions that can have similar symptoms. Researchers will combine information from genetic testing, lung imaging, and lung function tests to diagnose ant tell the difference between these two conditions. Participants in this study must be 5 to 45 years old. This study is taking place at multiple locations in the United States and in Canada.
Child, Adult
Recruiting
Wisconsin
Does your developing baby have a heart defect? Have you had a stillborn baby?
This study tests a new technology to measure fetal heart activity and find possible problems early. These problems include fetal arrhythmia and conduction disorders such as Brugada syndrome. To participate in this study, you must be at least 18 years old and pregnant, and have one of five high-risk complications of pregnancy: a fetus with a major congenital heart defect, hydrops, or gastroschisis; a previous unexplained stillbirth; or twins who share a placenta. This study is located in Madison and Milwaukee, Wisconsin.
Adult, Older Adult
Female
Recruiting
Tennessee
Have you been diagnosed with orthostatic intolerance?
This study aims to find out how the body’s regulation of basic functions, such as heart rate and blood pressure, is altered in people who have orthostatic intolerance. This condition, which has an unknown cause, is characterized by a racing heartbeat, dizziness, lightheadedness, and other symptoms that occur when a person stands up. To participate in this study, you must be between 18 and 80 years old and have orthostatic intolerance. This study is located in Nashville, Tennessee.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
Are you an adult female with LAM? If so, you may be able to participate in this clinical study where researchers are observing patients who are taking or have taken a certain kind of medication, mammalian target of rapamycin (mTOR), to treat lymphangioleiomyomatosis, also known as LAM. You must be at least 18 years old to take part. The study is taking place at locations in California, Colorado, Florida, Georgia, Illinois, Massachusetts, Michigan, Minnesota, Missouri, New York, Ohio, Oregon, Pennsylvania, South Carolina, Tennessee, Texas, Utah, and Washington.
Adult, Older Adult
Female