Find NHLBI Clinical Trials

Search selected NHLBI-supported clinical trials and observational studies by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.

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Showing 1 - 10 out of 10 results
Recruiting
Minnesota
Are you a Minnesota resident with hypertrophic cardiomyopathy? This study aims to find out how common it is for people with hypertrophic cardiomyopathy to also have sleep apnea. Hypertrophic cardiomyopathy is a disease that causes the heart muscle to thicken. Participants will also wear a heart rhythm monitor to help researchers learn whether sleep apnea is linked to arrhythmia. The study seeks healthy volunteers as well as participants in the Hypertrophic Cardiomyopathy Registry. To participate in this study, you must not have had a catheter ablation procedure to treat atrial fibrillation, had surgery to replace your heart valves, or been treated for sleep apnea. The study is located in Rochester, Minnesota.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
California
Are you being treated for atrial fibrillation? This study aims to compare two types of ablation treatment for patients who continue to have symptoms of atrial fibrillation despite treatment with medicines. The two ablation procedures treat different areas of tissue. To participate in this study, you must be at least 21 years old. The study is located in Palo Alto and San Diego, California.
Adult, Older Adult
Recruiting
Massachusetts
Texas
Do you know someone who will be having heart surgery? This study aims to identify what genetic patterns might cause atrial fibrillation and other adverse events that happen after heart surgery. To participate in this study, you must be between 20 and 90 years old. The study is in three locations in Massachusetts and Texas.
Adult, Older Adult
Recruiting
Did you develop atrial fibrillation after coronary artery bypass graft (CABG) surgery? Did you develop atrial fibrillation after a coronary artery bypass grafting (CABG) surgery? This study is looking at how well oral anticoagulation medicines work to prevent complications, such as blood clots and heart attack, for patients who experience post-operative atrial fibrillation (POAF). This study is in multiple locations around the country.
Adult, Older Adult
Recruiting
New York
Are you an adult with atrial fibrillation who recently had a catheter ablation procedure? This study will investigate the effectiveness of an implantable cardiac monitor-guided device to monitor participants for recurrent atrial fibrillation following ablation. This study is located in Rochester, New York.
Adult, Older Adult
Recruiting
Massachusetts
Texas
Are you an adult planning to have heart surgery at Brigham and Women’s Hospital or Texas Heart Institute? This study is looking into the genetic causes of heart problems that can happen after heart surgery, such as atrial fibrillation, myocardial infarction, renal dysfunction, and heart failure. To participate in this study, you must be between 20 and 90 years old. This study takes place in Boston, Massachusetts; and Dallas and Houston, Texas.
Adult, Older Adult
Recruiting
Maryland
Has your doctor recommended right heart cardiac catheterization for you? This study is investigating new magnetic resonance imaging (MRI) techniques that use a guidewire to help position a heart catheter within the heart. MRI fluoroscopy shows pictures of the heart so that doctors can watch while they work. Using the guidewire during MRI may improve the procedure of heart catheterization. To participate in this study, you must be at least 18 years old, and your doctor must have recommended right heart catheterization for you. This study is located in Bethesda, Maryland.
Adult, Older Adult
Recruiting
Florida
Are you an adult who does not have high blood pressure and is interested in research? This study will investigate how the brain regulates the body’s response to stress and how infection with HIV or pre-hypertension affects regulation. Your heart and brain activity will be measured while you are at rest, during a mentally stressful task, and while you feel angry. The study will also test whether a breathing exercise improves regulation. People with and without HIV and pre-hypertension will be included. To participate in this study, you must be between 21 and 65 years old and not have high blood pressure. This study is located in Miami, Florida.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
Do you have a high-risk pregnancy? This study will investigate the use of a non-invasive scan called fetal magnetocardiography to detect potential problems in the fetus in five high-risk pregnancy conditions associated with stillbirth. The scan is normally used to look at fetal heart rhythms. To participate in this study, you must be at least 18 years old and pregnant with one of the following: having a stillbirth in a previous pregnancy, carrying identical twins, or having a fetus that has been diagnosed with major congenital heart disease, fetal hydrops, or fetal gastroschisis. This study takes place in Madison and Milwaukee, Wisconsin.
Female
Recruiting
Indiana
Are you a woman who is postmenopausal or a man older than 65? This study will investigate the effects of oral progesterone for older women and testosterone for older men on QT intervals. QT intervals that are increased by medicine can lead to dangerous heart rhythm problems. Researchers hope to learn more about why this happens and how to deliver safer doses. This study is located in Indianapolis, Indiana.
Adult, Older Adult
Accepting Healthy Volunteers