Clinical Trials

Are you an African American woman at risk for diabetes? This study is testing whether using mobile health technology, such as smartphone apps and activity monitors, can help increase physical activity in African American women who are at risk for diabetes. To participate in this study, you must be an African American woman between 25 and 75 years old, have evidence of insulin resistance, and live in Prince George’s County, Maryland, or Ward 5, 7, or 8 in Washington, D.C. This study is located in Bethesda, Maryland.

Do you have a heart or blood vessel disease, such as peripheral artery disease? This study aims to collect data and samples from people who have a heart or blood vessel disease. This may include blood tests, ultrasound exams, and heart and lung tests. Family members and healthy people may also participate. The results may help researchers better understand PAD and other heart and blood vessel diseases. Participants must be at least 2 years old. Women who are pregnant may not take part in some study activities. This study is located in Bethesda, Maryland.

Are you at least 21 years old and have heart failure? In this clinical trial, researchers want to understand why patients with heart failure have trouble exercising and doing some of their daily activities. To take part, you must be taking medication to treat your heart failure for at least 30 days. People without heart failure can also join the study. Participants will have images (MRI) taken as part of the study. The study is taking place in Baltimore, Maryland.

The purpose of this project is to test sleep reactivity as an independent cause of Shift Work Disorder (SWD). The primary hypothesis is that those with high sleep reactivity will show persistent SWD symptoms after experimental reduction of circadian misalignment, which will then be mitigated with CBT.

The purpose of this project is to test sleep reactivity as an independent cause of Shift Work Disorder (SWD).

Do you get less than 7 hours of sleep each day and take medicine for opioid use disorder (OUD)? This study is looking at how the brain systems that control sleep can affect medication-assisted treatment in people who have opioid use disorder. The study will test whether suvorexant can help improve sleep and reduce stress without interfering with treatments for OUD. To participate in this study, you must be 21 to 65 years old. This study takes place at various locations in Baltimore, Bel Air, and Elkton, Maryland.

Do you have mild sleep apnea, or do you just want to help research? This study aims to understand how mild sleep apnea and not getting enough sleep contribute to daytime sleepiness. The study will also test which of three different treatment programs is most effective at preventing daytime sleepiness. To participate in this study, you must be at least 18 years old. This study takes place in Detroit, Michigan.