Find NHLBI Clinical Trials

Search selected NHLBI-supported clinical trials and observational studies by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.

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Showing 1 - 5 out of 5 results
Recruiting
Florida
Are you an adult whose high blood pressure does not improve with lifestyle changes and medicines? This study will assess whether minocycline, an antibiotic with anti-inflammatory effects, can improve blood pressure control in patients who do not respond to medicines in combination with lifestyle changes, such as physical activity, weight loss, and healthy eating patterns. To participate you must be at least 18 years old and have high blood pressure that does not respond to treatment with three different high blood pressure medicines even when used at the maximum doses. Please note that this study is in Gainesville, Florida.
Adult, Older Adult
Recruiting
Florida
Do you want to help researchers understand the link between gut bacteria and high blood pressure? This study aims to explore the relationship between gut microbiota (tiny organisms that live in the digestive system) and high blood pressure. The researchers will compare gut microbiota in participants with normal blood pressure, controlled high blood pressure, uncontrolled high blood pressure, and high blood pressure that is resistant to treatment. To participate in this study, you must be between 18 and 80 years old and not be pregnant or taking an antibiotic. This study is located in Gainesville, Florida.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
Florida
Are you an adult who does not have high blood pressure and is interested in research? This study will investigate how the brain regulates the body’s response to stress and how infection with HIV or pre-hypertension affects regulation. Your heart and brain activity will be measured while you are at rest, during a mentally stressful task, and while you feel angry. The study will also test whether a breathing exercise improves regulation. People with and without HIV and pre-hypertension will be included. To participate in this study, you must be between 21 and 65 years old and not have high blood pressure. This study is located in Miami, Florida.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
Florida
Do you have high blood pressure or want to help people who do? This study is looking at the role of the gut microbiome in controlled and uncontrolled high blood pressure. Participants in this study will provide blood and stool samples to help researchers learn more about this connection. To participate in this study, you must be between 18 and 80 years old. This study takes place in Gainesville, Florida.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
Florida
Are you an adult with high blood pressure? Some people with high blood pressure that does not respond well to medicine have a condition called neurogenic hypertension. This condition occurs when the nervous system becomes dysregulated as a result of high blood pressure. This study is examining the use of a new medicine to treat this condition called minocycline. To participate in this study, you must be between 18 and 85 years old and currently taking medicine to treat your high blood pressure. This study takes place in Gainesville, Florida.
Adult, Older Adult