Clinical Trials and Studies

Do you have cholesterol deposits in your heart arteries and you don’t take medicine to lower your cholesterol? This study is educating people with cholesterol deposits in their heart about the importance of taking medicines to lower cholesterol to prevent heart attacks and other heart diseases. To participate in this study, you should be 18 to 75 years old and have heart disease. This study is in Durham, North Carolina.

Are you interested in helping researchers learn more about how inflammation and diseases of the blood vessels start? Diseases related to the immune system, blood clots, and blood vessels are interrelated. This study is trying to understand how these diseases start and what happens in the different organs in people with these diseases. To participate in this study, you or your child should be 5 years old or older and be healthy or have an autoimmune disease, or problems with blood clots or blood vessels. This study is in Bethesda, Maryland.

Do you have both type II diabetes and obesity? Researchers are studying how exercise and weight-loss affect body fat tissues and cells in the body. Participants must be 18 to 50 years old and be able to do moderately intense physical activity. The study is taking place in Chicago, Illinois.

Are you a Hispanic father with a child between 5 and 11 years old? If so, would you be interested in learning how to prevent obesity for you and your child? Researchers are studying whether a father-child together program helps Hispanic dads and their children learn and use healthy behaviors to prevent obesity. You may be able to join if you are 65 or younger and have a child who is between 5 and 11 years old. Stepfathers, grandfathers, uncles, or older brothers may be able to join as well. The study is taking place in Houston, Texas.

Do you live in Appalachian Kentucky? Researchers will be using a phone app and incentives to provide health coaching. Participants will be encouraged to eat more fruits and vegetables and reduce saturated fats and screen time. They will also monitor your physical activity using a motion device and help you become more active. To join, you must be 18 years or older. The study is taking place in Benham, Kentucky.

Are you an adult with overweight or obesity? Researchers are studying a program that helps with physical activity. To join, you need a computer or smart phone and Wi-Fi. You must also be exercising less than 150 hours a week and not be in any weight loss or exercise programs. The study is in Aurora, Colorado.

Would you like more support with your heart and metabolic health? Would you like more support with your heart and metabolic health? This study will provide patients with personalized information about community-based resources to support health-related social needs and heart and metabolic health. You may be able to participate if you are 2 years or older, African American or Black, and you have at least one cardiometabolic condition. Conditions may include being overweight, having high blood pressure, pre-diabetes or diabetes, and/or high cholesterol. This study is recruiting in Rocky Mount, North Carolina.

Do you have asthma and are you overweight? This study aims to determine if metformin, a diabetes medicine, is effective in improving asthma conditions in individuals who are overweight or who have obesity. To enroll in this study, you must be an adult with poorly controlled asthma and your body mass index should be above 25.

People with obesity have a high risk for cardiovascular disease (CVD). People with obesity have a high risk for cardiovascular disease (CVD). Some hormones in the body, called natriuretic peptides, help lower your risk of CVD. When these hormones are low, they increase the risk of developing diabetes and poor heart health. This can lead to an increased risk of developing CVD. This study looks at how lower levels of the hormones made by the heart contribute to heart health. You may be able to participate if you are 18 years old or older, you will allow the collection of genetic material, and you are willing to follow the study protocol that includes an exercise regimen. This study is recruiting in Birmingham, Alabama.

Do you have obesity? Do you have obesity? Obese individuals also have lower levels of circulating Natriuretic Peptides. Natriuretic Peptides are hormones produced by the heart, which directly regulate non-dipping blood pressure by causing dilation of blood vessels and by removing sodium and water from the body. This study is evaluating the effect of the timing of administration of a medication that helps many people with obesity. To participate in the study, you must be 18 years or above and your body mass index should be between 30 to 45. This study is located in Birmingham, Alabama.