Clinical Trials

Are you an adult with both asthma and obesity? This study is testing whether a medicine called L-citrulline can help treat asthma and improve lung function in people who have obesity. To participate in this study, you must be 18 to 65 years old and have asthma and obesity. This study takes place in Durham, North Carolina.

Has your child been treated for an asthma attack with an oral corticosteroid medicine in the last 12 months? A study team will recruit 60 teens and young adults (between 12 and 21 years old) with persistent asthma who are at high risk for future exacerbation. This study examines the contribution of interleukin 1 beta (IL-1β), a protein that is involved in the inflammatory response, in asthma flare-ups. This study takes place in Chapel Hill, North Carolina.

Has your doctor recommended right heart cardiac catheterization for you? This study is investigating new magnetic resonance imaging (MRI) techniques that use a guidewire to help position a heart catheter within the heart. MRI fluoroscopy shows pictures of the heart so that doctors can watch while they work. Using the guidewire during MRI may improve the procedure of heart catheterization. To participate in this study, you must be at least 18 years old, and your doctor must have recommended right heart catheterization for you. This study is located in Bethesda, Maryland.

Are you an adult who does not have high blood pressure and is interested in research? This study will investigate how the brain regulates the body’s response to stress and how infection with HIV or pre-hypertension affects regulation. Your heart and brain activity will be measured while you are at rest, during a mentally stressful task, and while you feel angry. The study will also test whether a breathing exercise improves regulation. People with and without HIV and pre-hypertension will be included. To participate in this study, you must be between 21 and 65 years old and not have high blood pressure. This study is located in Miami, Florida.