Clinical Trials

Do you have heart disease? This study is looking to improve the quality of heart CT scans by using new methods to create the images. You may be able to participate in the study if you are 18 years old or older, have heart disease, and have been told by your doctor that you need a CT scan. This study is taking place at the National Institutes of Health Clinical Center in Bethesda, Maryland.

Do you have mitral valve disease? This clinical trial is testing different types of images taken of the heart to learn more about mitral valve disease and the best ways to treat it. You must be 60 years old to participate. The study is enrolling patients in locations in Arkansas, California, Georgia, Indiana, Louisiana, Maine, Maryland, Massachusetts, Michigan, Missouri, New York, North Carolina, Ohio, Pennsylvania, and Quebec City, Canada.

Have you ever had a percutaneous coronary intervention (PCI), which is a procedure used to open clogged coronary arteries? Researchers in this clinical trial are studying the genes of people who have had PCI to learn the best way to prescribe medication after the procedure. Participants must be 18 and must have had PCI and received antiplatelet therapy, like aspirin, following the procedure. The trial is taking place in Gainesville, Florida.

Do you have coronary heart disease or are you healthy and would like to participate in research? This study is comparing how well two types of magnetic resonance imaging (MRI) scanners can detect different types of heart diseases, such as coronary heart disease, heart failure, congenital heart disease, and heart valve disease. The new type of MRI scanner in this study uses less energy than a traditional scanner and may be suitable for people who have metal devices in their bodies. This study is located in Bethesda, Maryland.

Do you or your child have cardiovascular disease or want to help research? This study aims to improve cardiac magnetic resonance imaging (MRI) techniques. The clinical investigators will use new MRI methods to look at healthy people and people who have heart problems. Participants in this study must be at least 7 years old, be healthy or have cardiovascular disease, and not be pregnant. This study is located in Bethesda, Maryland.

Do you or your child have cardiovascular disease or want to help research? This study aims to identify better MRI methods and new ways of imaging cardiovascular disease to understand cardiovascular and brain function. Researchers are also interested in seeing whether gadolinium, the commonly used MRI contrast agent, stays in the body long after an MRI is performed. To participate in this study, you or your child should be healthy or have a cardiovascular condition and be at least 7 years old.

Do you or your child have a disease affecting the blood vessels? This study is collecting blood samples to study the role of inflammation in diseases of the blood vessels, including coronary heart disease and sickle cell disease. To participate, you or your child must be at least 2 years old and either be healthy or have a disease affecting the blood vessels. This study is located in Bethesda, Maryland.

Are you able to have a magnetic resonance imaging (MRI) scan and want to help people with heart failure? This study is developing new methods for imaging the heart and blood vessels using MRI to improve how healthcare providers diagnose people with heart failure. This study takes place in Maryland and Washington, DC.

Do you have a scheduled CT scan for heart disease? This study will look at different ways to take pictures of the heart and blood vessels using computed tomography (CT) that use less radiation than traditional scans. This study is located at the NIH Clinical Center in Bethesda, Maryland.

Is your newborn in the NICU at Holtz Children’s Hospital in Miami? Newborns born very prematurely often need oxygen therapy or ventilation to help them breathe and survive. This study will help doctors understand how changes in oxygen and carbon dioxide levels while newborns are getting treatment affect how their lungs develop. While your newborn is in the newborn neonatal intensive care unit (NICU), researchers will record his or her oxygen and carbon dioxide levels, heart rate, and other measures. To participate in this study, your newborn must have been born prematurely between 23 and 28 weeks’ gestation, be less than 28 days old, and be receiving oxygen therapy. This study is located in Miami, Florida.