Clinical Trials

Are you or your child at least 13 years old and have sickle cell disease? In this stidy, researchers are trying to find out if a new medication improves the success of a blood stem cell transplant. People 13 years old or older who are eligible for a blood stem cell transplant to treat sickle cell disease may be able to participate. Healthy family members over age 13 who are matched to transplant recipients are also needed to donate blood for the study. This study is taking place at the National Institutes of Health Clinical Center in Bethesda, Maryland.

This research study is designed to learn, first, whether two anesthetics have different effects on collapse seen within the upper airway during sleep endoscopy.

Are you a parent of a child in kindergarten to 5th grade? Or do you lead teachers who teach children in these grades? Researchers are testing if active learning can get children to move more. Active learning blends physical activity into school lessons. The study is taking place in Houston, Texas.

The researchers are investigating if the Self-Supporting Nasopharyngeal Airway (ssNPA) device can be used in the treatment of obstructive sleep apnea in children with Hypotonic Upper Airway Obstruction (HUAO).

The purpose of this study is to non-invasively characterize the fibrotic consequences of single ventricle physiology, its possible solution and effect on lymphatics.

The goal of the study is to learn more about tests that can assess lung health in children with Down syndrome.

The purpose of this trial is to evaluate if augmenting a usual audit and feedback implementation approach with telehealth-enabled support improves coordinated spontaneous awakening/breathing trials and patient outcomes for mechanically ventilated patients.

Does your child have Down Syndrome? Did they have a complete atrioventricular septal defect (CAVSD) repair within the first year of their life? Researchers in this study are investigating how the
brain develops in children with Down Syndrome who have congenital heart disease. To participate, your child must be between 5 and 12 years old and have Down Syndrome. The study will enroll children who have congenital heart disease as well as children who do not have congenital heart disease. The study is taking place in locations in Delaware, Georgia, Indiana, Massachusetts, Michigan, Missouri, New York, Ohio, Pennsylvania, South Carolina, Texas, Utah, Washington, D.C., and Toronto, Canada

Are you a Hispanic father with a child between 5 and 11 years old? If so, would you be interested in learning how to prevent obesity for you and your child? Researchers are studying whether a father-child together program helps Hispanic dads and their children learn and use healthy behaviors to prevent obesity. You may be able to join if you are 65 or younger and have a child who is between 5 and 11 years old. Stepfathers, grandfathers, uncles, or older brothers may be able to join as well. The study is taking place in Houston, Texas.

Does your child have asthma? If so, they may be eligible to participate in a study about whether using a smartphone application can improve asthma management. To participate, your child must be between the age of 12 and 18 and have an iPhone or Android device on which an app can be installed. The study is taking place at the University of South Florida in Tampa, Florida, and participants are expected to remain in the Tampa Bay area for the duration of the study.