Zhao In the News
This systems biology study cataloged over 1500 long noncoding RNA molecules (lincRNAs) present in T-cells. The findings reveal that lincRNAs have co-evolved with neighboring protein-coding genes, and provide important clues into the function and regulation of these intriguing molecules.
Scientists may have discovered why a protein called MYC can provoke a variety of cancers. Like many proteins associated with cancer, MYC helps regulate cell growth. A study carried out by researchers at the National Institutes of Health and colleagues found that, unlike many other cell growth regulators, MYC does not turn genes on or off, but instead boosts the expression of genes that are already turned on.
These findings, which will be published in Cell on Sept. 28, could lead to new therapeutic strategies for some cancers.
The working group concluded that epigenetics research should incorporate multispecies comparisons to benefit from evolutionary insights and perspectives. Studies will require coordination of multidisciplinary teams combining expertise in clinical and basic research, as well as in computational and modeling methods.