NHLBI IN THE PRESS

Super-bright, biodegradable nanoparticles hold promise for safe, sensitive optical imaging

Researchers standing and conversating.

Researchers have developed a new, highly sensitive, super-bright, long-lasting optical imaging approach that overcomes the limitations of previous molecular imaging tools. Specifically, they designed safe, biodegradable semiconducting polymer nanoparticles for visualizing tumors, monitoring disease progression, and other imaging applications in living organisms. They demonstrated the usefulness of the approach for imaging tumors and real-time monitoring of drug-induced liver toxicity in living mice. The study, published in Nature Biotechnology, was partly funded by NHLBI.

Nanotechweb.org: Polymer nanoparticles make good afterglow agents