The National Institutes of Health’s (NIH) National Heart, Lung, and Blood Institute (NHLBI), in partnership with eight other NIH institutes, convened a workshop on Identifying Research Opportunities for Asian American, Native Hawaiian, and Pacific Islander (AsA and NHPI) Health. The workshop assembled national experts from multiple disciplines to review current research and identify knowledge gaps, potential barriers, and opportunities for prevention research to improve health equity for AsA and NHPI populations.
In 2019, ASA and NHPI comprised 6% of the total U.S. population (23.2 million AsA and 1.5 million NHPI). Over the last two decades, Asian Americans have been the fastest growing subpopulation in the United States (95% increase), and the total AsA population is expected to surpass 46 million by 2060. AsA and NHPIs are highly diverse linguistically, culturally, and demographically. However, in most national surveys, reports, and studies, these groups are aggregated, masking health disparities in specific groups. And over the past 25 years, NIH has invested only 0.17% of its budget in AsA and NHPI health research.1
The objectives of this workshop were to:
The workshop covered five domain areas: social, cultural, psychological, and lifestyle determinants of health; metabolic disorders; cardiovascular and lung diseases; cognitive function and healthy aging; and cancer.
The recurring themes from discussions across domains were:
There is an urgent need for research that focuses on specific AsA and NHPI subgroups to provide insight into the epidemiology and etiology of common or high-risk health conditions to inform prevention, treatment, and patient care to improve health equity in these populations.
Below is a short list of research opportunities and strategies to improve the quality and impact of health research among AsA and NHPI populations discussed at the workshop.
I. Build infrastructure for studies in AsA and NHPI population groups.
Develop a state-of-the-art research infrastructure to serve as the platform to coordinate, collaborate, and implement innovative research in AsA and NHPI populations. Partner with AsA and NHPI communities to enhance study participant engagement, recruitment and retention, study implementation, and outcome dissemination.
II. Incorporate novel technologies in exposure assessment and clinical evaluation.
Leverage modern imaging techniques and digital technology for exposure and outcome assessment to advance health research and clinical care in AsA and NHPI populations.
III. Investigate how sociocultural determinants influence health, prevention, and outcomes.
Develop studies to better understand the impact of socioeconomic status, language use, culture and acculturation, and social networks on health disparities in AsA and NHPI groups.
In summary, the workshop identified gaps, barriers, and research opportunities in these diverse populations. It highlighted common themes across different disease domains, and emphasized the importance of working together and with community partners to advance science and health equity for AsA and NHPI populations.
The meeting organizers and participants will develop a workshop report for submission for publication in a peer-reviewed journal. The report will describe in more depth the discussions and research opportunities, including those under each of the five domain areas.
1 Trends in Clinical Research Including Asian American, Native Hawaiian, and Pacific Islander Participants Funded by the US National Institutes of Health, 1992 to 2018: JAMA Network Open; 2019 Jul 3;2(7):e197432. doi: 10.1001/jamanetworkopen.2019.7432. (PubMed)
Alka M. Kanaya, MD, University of California, San Francisco
Ann Hsing, PhD, MPH, Stanford University
Rosario (Happy) G. Araneta, PhD, MPH, University of California, San Diego
Martha L. Daviglus, MD, PhD, University of Illinois College of Medicine
Scarlett Lin Gomez, PhD, MPH, University of California, San Francisco
Frank Hu, MD, PhD, MPH, Harvard University
Nadia S. Islam, PhD, New York University
Chandra L. Jackson, PhD, MS, National Institute of Environmental Health Sciences, NIH
Namratha R. Kandula, MD, MPH, Northwestern University
John “Keoni” S.K. Kauwe, PhD, Brigham Young University, Oahu
Marjorie K. Leimomi Mala Mau, MD, University of Hawai’i at Mānoa
Jinkook Lee, PhD, University of Southern California
Kiang J. Liu, PhD, Northwestern University
Simin Liu, MD, MPH, ScD, Brown University
Grace X. Ma, PhD, Temple University
K. M. Venkat Narayan, MD, MSc, MBA, Emory University
Tung Nguyen, MD, University of California, San Francisco
Latha Palaniappan, MD, MS, Stanford University
Sela V. Panapasa, PhD, University of Michigan
Ninez Ponce, MPP, PhD, University of California, Los Angeles
Raynald Samoa, MD, City of Hope Comprehensive Cancer Center
V. Wendy Setiawan, MS, PhD, University of Southern California
Sono Shah, PhD, Pew Research Center
Svati H. Shah, MD, MHS, Duke University School of Medicine
Chau Trinh-Shevrin, DrPH, New York University
Daichi Shimbo, MD, Columbia University
Janice Y. Tsoh, PhD, University of California, San Francisco
Dhananjay Vaidya, MBBS, PhD, MPH, Johns Hopkins University
Barbara Vickrey, MD, MPH, The Mount Sinai Hospital
Paul J. Wang, MD, Stanford University
Thomas Wang, MD, University of Texas Southwestern Medical Center
Nathan D. Wong, PhD, MPH, University of California, Irvine
Merle Kataoka-Yahiro, DrPH, MS, APRN, University of Hawai’i at Mānoa
National Heart, Lung, and Blood Institute (NHLBI)
Division of Cardiovascular Sciences (DCVS)
Yuling Hong, MD, MSc, PhD (Workshop Co-Leader)
Sean Coady, MA, MS (Workshop Co-Leader)
Alison Brown, MS, PhD
David Goff, MD, PhD
Meagan G. Grant, PhD
Mona Puggal, MPH, MBA, PMP
Jared P. Reis, PhD
Division of Lung Diseases
Marishka Brown, PhD
Qing Lu, DVM, PhD
Aruna Natarajan, MD, PhD
Koyeli Banerjee, PhD
National Cancer Institute
Tram Kim Lam, PhD, MPH, Division of Cancer Control and Population Sciences
Pothur Srinivas, PhD, Division of Cancer Control and Population Sciences
National Eye Institute
Mary Frances Cotch, PhD, Office of Vision Health and Population Sciences
National Human Genome Research Institute
Teri Manolio, MD, PhD, Division of Genomic Medicine
Renee Rider, JD, MS, CGC, Division of Genomic Medicine
National Institute of Aging
Dallas Anderson, PhD, Division of Neuroscience
Marilyn M. Miller, PhD, Division of Neuroscience
National Institute of Diabetes and Digestive, and Kidney Diseases
Beena Akolkar, PhD, Division of Diabetes, Endocrinology, & Metabolic Diseases
Barbara Linder, PhD, Division of Diabetes, Endocrinology, & Metabolic Diseases
Susan Yanovski, PhD, Office of Obesity Research and Division of Digestive Diseases & Nutrition
National Institute of Mental Health
Dawn Morales, PhD, Office of Rural Mental Health Research
National Institute of Minority Health and Health Disparities
Larissa Avilés-Santa, MD, MPH, Division of Scientific Programs
Rina Das, PhD, Division of Extramural Scientific Programs
Tilda Farhat, PhD, MPH, Office of Science Policy, Planning, Evaluation, and Reporting
National Institute of Neurological Disorders and Stroke
Richard T. Benson, MD, PhD, Office of Global Health and Health Disparities
Stacey D. Chambers, MS, Office of Global Health and Health Disparities
Naomi E. Booker, MPH, Office of Global Health and Health Disparities
Erica L. Littlejohn, PhD, Office of Global Health and Health Disparities