Translation Research Branch

To build on the successes in fundamental discovery science and early-stage translational research, it is important to facilitate late-stage T4 translational research—the phase in the translational research pathway that leads to general knowledge about implementing evidence-based interventions—that helps turn discoveries into improved health. Successful execution of T4 translation research requires the transdisciplinary collaboration of diverse stakeholders across various sectors. Innovative platforms can be developed to solicit, nurture, and support team science while leveraging expertise from biomedical, behavioral, and social science research, as well as experts from engineering, bioinformatics, behavior economics, and the emerging field of big data science. 

Our Programs

T4 Research Program

This program serves as the core opportunity to support T4 translation research in heart, lung, blood, and sleep disorders, with implementation research outcomes as primary endpoints. This program will advance our understanding of implementation strategies across diverse patient populations and health systems. It also will significantly impact care of heart, lung, blood, and sleep disorders by decreasing the ‘gap in translation’ from clinical trials and academic centers to communities where most health services are delivered. 


Small Business Topic of Special Interest Program

This program leverages the Institute’s Small Business grant mechanisms to support the development of innovative technology, service delivery models, or designs to increase the adoption, uptake, and sustainability of evidence-based guideline recommendations for the management of heart, lung, blood, and sleep disorders. These technologies or service delivery models should include multi-level (health systems, provider, and patient) facets and benefit certain populations, such as racial or ethnic minority groups, rural populations, and low socioeconomic status groups. 


Contact Translation Research Branch

Postal Mail

Center for Translation Research and Implementation Science - Translation Research Branch
National Heart, Lung, and Blood Institute
Rockledge I, 6705 Rockledge Drive, 4th floor, MSC 7960
Bethesda, MD 20892-7960
United States