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July 1, 2014
Adults stop anti-rejection drugs after partial stem-cell transplant reverses sickle cell disease
Half of patients in a trial have safely stopped immunosuppressant medication following a modified blood stem-cell transplant for severe sickle cell disease, according to a study in the July 1 issue of the Journal of the American Medical Association. The trial was conducted at the National Institutes of Health’s Clinical Center in Bethesda, Maryland, by researchers from NIH’s National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and the National Heart, Lung, and Blood Institute.

May 19, 2014
Common treatment for patients with chronic, progressive lung disease found to be ineffective
A drug used to treat patients with mild to moderate lung damage from the disease idiopathic pulmonary fibrosis (IPF) is no better than placebo for preserving lung function, according to a study supported by the National Institutes of Health. The finding is in the final report of a clinical trial called Prednisone, Azathioprine, and N-Acetylcysteine: A Study That Evaluates Response in Idiopathic Pulmonary Fibrosis (PANTHER-IPF).

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Spotlight On Research

Featured Fact Sheet

images of the reduction in blood flow after a mental stress test compared to after a physical stress test and at rest

Emotional stress and heart disease in women: an interview with Dr. Viola Vaccarino
When it comes to the effects of emotional stress on the heart, young men and women may not be created equal. Understanding the role of emotional factors—in particular psychological stress—on heart disease risk is a professional passion for longtime NHLBI grantee, Dr. Viola Vaccarino, a leader in women’s health research. Read full fact sheet...


NHLBI In The News rss feed

August 12, 2014 : Triad Business Journal
Wake Forest Baptist receives $7M grant for lung injury clinical trials
Owen Covington
Wake Forest Baptist Medical Center will receive a $7 million, seven-year grant from the National Heart, Lung, and Blood Institute as part of a broader network of research centers that is looking at the prevention and early treatment of acute lung injury.

August 11, 2014 : Indiana University School of Medicine
Newly discovered heart molecule could lead to effective treatment for heart failure
Researchers at the Indiana University School of Medicine have discovered a previously unknown cardiac molecule that could provide a key to treating, and preventing, heart failure. The work was partially funded by the National Heart, Lung, and Blood Institute.

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Upcoming Events

September 17, 2014 - September 18, 2014
NHLBI Annual Sickle Cell Disease Clinical Research Meetings
Bethesda, Maryland

The Annual Sickle Cell Disease Clinical Research Meetings provide a venue for study investigators to meet and review progress in ongoing and proposed clinical trials.


September 18, 2014 - September 19, 2014
Small Blood Vessels: Big Health Problems?
Bethesda, MD

This two-day conference will bring together scientists and clinicians from diverse areas of small blood vessel research to share their latest discoveries, identify common challenges, and foster collaborative research on the normal function and malfunction of small blood vessels in the brain, heart, lung, kidney, eye, and other organs.


September 22, 2014 - September 22, 2014
NHLBI Regional Innovation Conference
Research Triangle Park, NC

NHLBI’s Office of Translational Alliances and Coordination (OTAC) hosts this semi-annual Regional Innovation Conference that brings together small businesses, angel investors, venture capitalists, strategic partners, and business leaders from the biotech, medical device, and pharmaceutical industries. NHLBI staff will be available to describe the details and impact of recent changes in the Federal SBIR/STTR program, as well as other funding opportunities and resources for small businesses.


Director's Message
Why Do Fruit Flies Take Naps? NHLBI Investigator Studies Connections Between Sleep Patterns and Gene Networks in Fruit Flies

Gary H. Gibbons
August 19, 2014

When NIH researchers talk about genome-wide association studies (GWAS), they’re often talking about research that compares DNA markers across the genome in people with a disease to people without the disease. In the case of NHLBI’s Dr. Susan Harbison, she’s most likely talking about the DNA and genome of Drosophilia, aka, the common fruit fly....
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