NHLBI-supported study finds that among young children with histories of recurrent severe lower respiratory tract illnesses (RTI), the use of azithromycin early during an apparent RTI compared with placebo reduced the likelihood of severe lower respiratory tract illnesses.
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Specific dosage of sickle cell drug increases survival rate
WHAT: An analysis by National Institutes of Health researchers has shown that people with sickle cell anemia who took the drug hydroxyurea at the recommended dose had higher survival rates than those who took less than the recommended dose. The findings appear in the journal PLOS ONE.
NIH researchers find potential target for reducing obesity-related inflammation
Scientists at the National Institutes of Health have identified a potential molecular target for reducing obesity-related inflammation. Researchers have known that overeating (that is, excess calorie consumption) by individuals with obesity often triggers inflammation, which has been linked to such diseases as asthma and Type 2 diabetes. In their study, published recently in The Journal of Clinical Investigation (Nov.
Featured Fact Sheet
In 2010, Afia Donkor, a young woman from Canada, struggled to walk a few blocks from her home to a subway station in Montreal on her way to the airport. Suitcase in hand, she moved at a snail’s pace as she experienced severe exhaustion due to a flare-up of her sickle cell disease. One step at a time, she finally made it, propelled by the hope of a new treatment that awaited her at the other end of her journey to the United States. Read full fact sheet...
A federally funded analysis of MRI scans of the aging hearts of nearly 3,000 adults shows significant differences in the way male and female hearts change over time. Results of the research, led by investigators at Johns Hopkins with funding from NHLBI, do not explain exactly what causes the sex-based differences but they may shed light on different forms of heart failure seen in men and women that may require the development of gender-specific treatments, the scientists say.