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The first lung-related symptoms of AAT deficiency may include shortness of breath, less ability to be physically active, and wheezing. Some people may not have any symptoms or complications. AAT deficiency can lead to lung and liver diseases.
Symptoms of AAT deficiency include:
These symptoms usually appear in people between 20 and 50 years old. At first, many people who have AAT deficiency are diagnosed with asthma. This is because wheezing also is a symptom of asthma. Also, people who have AAT deficiency respond well to asthma medicines.
Some people who have AAT deficiency may have liver damage. Signs of liver damage include jaundice and swelling in your legs. Rarely, AAT deficiency can cause skin problems, such as painful lumps or patches.
AAT deficiency can lead to:
Early diagnosis can help you prevent serious complications by avoiding risk factors such as smoking.