Triglycerides >1,500 mg/dL Research Study - Diagnosis and Followup Protocol
If you have triglycerides >1,500 mg/dL (hypertriglyceridemia) that occurred before you were 25 years old or had pancreatitis as a child with elevated triglycerides, you are invited to participate in a study in an attempt to diagnose and follow your disorder. There are several known causes of high triglycerides in childhood and they include Lipoprotein Lipase (LPL) deficiency and Apolipoprotein C-II (apoC-II) deficiency. However, other causes of high triglycerides in childhood have yet to be discovered. You are not eligible if the high triglycerides occurred only in adulthood (>30 years), or if you are an adult with obesity, diabetes, or drink excessive alcohol.
Eligible persons will undergo a comprehensive evaluation at no cost to you. All patients will remain under the care of their own physician who will receive results of the laboratory and diagnostic tests. In many cases, you will be invited back for yearly evaluations related to other studies. There is no cost to you for travel and for some of your medications.
For further information please contact our research coordinator (tel. 301-496-1500, e-mail: LipidStudy@nhlbi.nih.gov).