The National Heart, Lung, and Blood Institute (NHLBI) and other National Institutes of Health (NIH) Institutes and Centers sponsor clinical trials.
Many other groups, companies, and organizations also sponsor clinical trials. Examples include Government Agencies, such as the U.S. Departments of Defense and Veterans Affairs; private companies; universities; and nonprofit organizations.
NIH Institutes and Centers (including the NHLBI) usually sponsor trials that test principles or strategies. For example, one NHLBI study explored whether the benefits of lowering high blood pressure in the elderly outweighed the risks.
Other examples of clinical trials that test principles or strategies include studies that
- explore whether surgery or other medical treatments produce better results for certain illnesses or groups of people;
- look at the best age and frequency for doing screening tests, such as mammography; and
- compare two or more screening tests to see which test produces the best results.
Some companies and groups sponsor clinical trials that test the safety of products, such as medicines, and how well they work. The U.S. Food and Drug Administration (FDA) oversees these clinical trials. The NIH may partner with these companies or groups to help sponsor some trials.
All types of clinical trials contribute to medical knowledge and practice.
Children and Clinical Studies: Messages for researchers08/15/2013
In this video, more than a dozen pediatric clinician-researchers, doctors, and nurses talk about the importance of conducting clinical trials for children and their own motivations for pursuing research in this field.
Children and Clinical Studies: For parents and caregivers08/15/2013
In this video, more than a dozen pediatric clinician-researchers, doctors, and nurses talk about the importance of conducting clinical trials for children while addressing common questions that parents and caregivers face when they are considering enrolling a child in a clinical study.
Children are not little adults, yet they are often given medicines and treatments that were only tested in adults. The way to get the best treatments for children is through research designed specifically for them.
The National Institutes of Health (NIH) remains committed to ensuring that families get all the information they need to feel comfortable and make informed decisions. The safety of children is the utmost priority for all NIH research studies.