The NHLBI Murine Phenotyping Core carries out physiologic and behavioral testing in a diversity of mouse models for NHLBI and other NIH institutes.
Testing Areas include the following:
- Cardiovascular Phenotyping
- Metabolic Phenotyping
- Pulmonary Phenotyping
- Neuromuscular Phenotyping
- Behavioral Phenotyping
- Exercise Physiology
- Advanced Imaging Modalities (whole body high frequency ultrasound imaging, vascular imaging, faxitron x-ray, and CT (coming soon))
Nat Commun 2014 Jan 01;5:4930.
The physiological role of mitochondrial calcium revealed by mice lacking the mitochondrial calcium uniporter.
Nat Cell Biol 2013 Dec 02;15(12):1464-72.
Increased mammalian lifespan and a segmental and tissue-specific slowing of aging after genetic reduction of mTOR expression.
Cell Rep 2013 Sep 13;4(5):913-20.
N Engl J Med 2013 Mar 15;368(11):1027-32.
Deletion of iron regulatory protein 1 causes polycythemia and pulmonary hypertension in mice through translational derepression of HIF2α.
Cell Metab. 2013 Feb 06;17(2):271-81.
Cell Metab. 2012 Aug 08;16(2):167-79.