- Murine Phenotyping Core Research
The NHLBI Murine Phenotyping Core carries out physiologic and behavioral testing in a diversity of mouse models for NHLBI and other NIH institutes.
Testing Areas include the following:
- Cardiovascular Phenotyping
- Metabolic Phenotyping
- Pulmonary Phenotyping
- Neuromuscular Phenotyping
- Behavioral Phenotyping
- Exercise Physiology
- Advanced Imaging Modalities (whole body high frequency ultrasound imaging, vascular imaging, faxitron x-ray, and CT (coming soon))
Investigation and identification of etiologies involved in the development of acquired hydronephrosis in aged laboratory mice with the use of high-frequency ultrasound imaging.
Pathobiol Aging Age Relat Dis 2016 Aug 01;4.
J Mol Med (Berl) 2016 Mar 01;94(3):277-86.
Mice expressing reduced levels of hepatic glucose-6-phosphatase-α activity do not develop age-related insulin resistance or obesity.
Hum Mol Genet 2015 Sep 15;24(18):5115-25.
J Mol Cell Cardiol 2015 Aug 01;85:178-82.
SMAD3 negatively regulates serum irisin and skeletal muscle FNDC5 and peroxisome proliferator-activated receptor γ coactivator 1-α (PGC-1α) during exercise.
J Biol Chem 2015 Mar 20;290(12):7671-84.
PLoS One 2015 Jan 01;10(1):e0115861.