Christian Combs received his B.S. in Zoology from the University of Florida in 1989, his M.S. in Zoology from Auburn University in 1994, and his Ph.D. in Biological Science from the Florida State University in 1996. He was a Postdoctoral Fellow at the NIH in the NHLBI Lab of Cardiac Energetics (LCE) from 1996-1999 and briefly a Staff Fellow in the LCE in 2000. He has been the Director of the NHLBI Light Microscopy Core since its start in 2000. His memberships have included the American Physiological Society and the Biophysical Society.
The NHLBI Light Microscopy Core (LMC) consists of three people (Dr. Christian A. Combs (Director), Dr. Daniela A. Malide, and Dr. Xufeng Wu (Deputy Director)) and nineteen microscopes located in buildings 10 and 50 on the main NIH campus in Bethesda, MD. The mission of the LMC is to provide state-of-the-art equipment, training, and image processing capabilities to assist NHLBI-DIR researchers in experiments involving light microscopy. To date we have helped researchers publish more than 350 papers. Research conducted by investigators using the LMC has been on many disease states, basic cell biology, and on development and implementation of new imaging methods. Researchers that work in this facility can expect support from core personnel to whatever level suits their research requirements. This can include advanced microscopy techniques like super-resolution and intra-vital two-photon microscopy to more ordinary confocal and wide-field imaging applications. In addition to the microscopes, we provide a full suite of image processing programs on several image processing workstations. In summary this facility operates with state-of-the-art equipment and a dedicated team of imaging professionals to further the research mission of the NHLBI-DIR.