Echocardiography

The Echocardiography Laboratory, led by Dr. Vandana Sachdev, performs comprehensive cardiac imaging for NHLBI and all institutes at the NIH Clinical Center.

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Research Interests

Research Interests

Representative research applications include:

  • 3D imaging for structural cardiac defects
  • Strain imaging for ventricular function
  • Contrast imaging for left ventricular size, function, and evaluation of intracardiac abnormalities
  • Contrast perfusion imaging of myocardium and skeletal muscle for the evaluation of microvascular flow
  • Protocol-specific imaging of patients with mitral regurgitation to evaluate newer methods for quantitation of regurgitation severity

Featured Publications

Broadening the spectrum of Ehlers Danlos syndrome in patients with congenital adrenal hyperplasia.

Authors: Morissette R, Chen W, Perritt AF, Dreiling JL, Arai AE, Sachdev V, Hannoush H, Mallappa A, Xu Z, McDonnell NB, Quezado M, Merke D
J Clin Endocrinol Metab 2015 Jun 15:jc20152232
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Detection of Trypanosoma cruzi DNA in blood by PCR is associated with Chagas cardiomyopathy and disease severity.

Authors: Sabino EC, Ribeiro AL, Lee TH, Oliveira CL, Carneiro-Proietti AB, Antunes AP, Menezes MM, Ianni BM, Salemi VM, Nastari L, Fernandes F, Sachdev V, Carrick DM, Deng X, Wright D, Gonçalez TT, Murphy EL, Custer B, Busch M
Eur J Heart Fail 2015 Apr 01;17(4):416-23
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Myocardial fat overgrowth in Proteus syndrome.

Authors: Hannoush H, Sachdev V, Brofferio A, Arai AE, LaRocca G, Sapp J, Sidenko S, Brenneman C, Biesecker LG, Keppler-Noreuil K
Am J Med Genet A 2015 Jan 01;167A(1):103-10
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Risk factors for death in 632 patients with sickle cell disease in the United States and United Kingdom.

Authors: Gladwin MT, Barst RJ, Gibbs JS, Hildesheim M, Sachdev V, Nouraie M, Hassell KL, Little JA, Schraufnagel DE, Krishnamurti L, Novelli E, Girgis RE, Morris CR, Berman Rosenzweig E, Badesch DB, Lanzkron S, Castro OL, Taylor JG 6th, Goldsmith JC, Kato GJ, Gord
PLoS One 2014 Jan 01;9(7):e99489
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Analysis of cardiac anomalies in VACTERL association.

Authors: Cunningham BK, Hadley DW, Hannoush H, Meltzer AC, Niforatos N, Pineda-Alvarez D, Sachdev V, Warren-Mora N, Solomon B
Birth Defects Res A Clin Mol Teratol 2013 Dec 01;97(12):792-7
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Meet the Team

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Vandana Sachdev, M.D.

Director

Vandana Sachdev, M.D., is the director of the Echocardiography Laboratory at the NHLBI.