Asthma is a common chronic disease without cure. Our understanding of asthma onset, pathobiology, classification, and management has evolved substantially over the past decade; however, significant asthma-related morbidity and excess healthcare use and costs persist. To address this important clinical condition, the NHLBI convened a group of extramural investigators for an Asthma Research Strategic Planning workshop on September 18–19, 2014, to accelerate discoveries and their translation to patients. The workshop focused on (1) in utero and early-life origins of asthma, (2) the use of phenotypes and endotypes to classify disease, (3) defining disease modification, (4) disease management, and (5) implementation research. This report summarizes the workshop and produces recommendations to guide future research in asthma.
Research Meeting Summaries
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The NHLBI convened this November 2014 workshop to discuss the results of recent research on the effects of inorganic nitrate and nitrite on the cardiovascular system.
During this November 2014 teleconference, federal agencies provided updates on their efforts to improve understanding, treatment, and awareness of COPD.
In September 2014, a working group identified challenges in the development and application of technologies for in-home care for older adults and those with chronic disabilities and recommended research priorities to advance the development of these technologies.
In September 2014, the NHLBI convened a group of experts in the areas of cardiovascular risk assessment, treatment of blood cholesterol to reduce cardiovascular risk, and implementation and dissemination to identify gaps in current lipid and cardiovascular disease risk assessment guidelines.
In August 2014, a working group recommended actions to advance COPD research through using existing resources and establishing new collaborations.
In July 2014, a working group identified knowledge gaps in our understanding of the natural history, diagnosis, and treatment of DMD-associated cardiac disease and developed a research agenda to address these gaps.
In June 2014, a working group recommended research topics that would benefit adults with congenital heart disease, who, thanks to improvements in treating congenital heart defects, represent a growing population.
The NHLBI convened a working group of multidisciplinary researchers in May 2014 to share current knowledge regarding the effects of dietary salt on the human body and to explore and identify scientific gaps in our understanding of how salt affects hypertension, the cardiovascular system, and immunity.