2016

Orloff Award Winners

Nihal Altan-Bonnet, Ph.D. is an Earl Stadtman investigator and the head of the Laboratory of Host-Pathogen Dynamics at the NHLBI. Her research focuses on better understanding the dynamic process of viral DNA replication within the host cell. Dr. Altan-Bonnet and her team won the Orloff Award for work on the mechanism of transmission of enteroviruses.

Brian Glancy, Ph.D. is a tenure track investigator in the Laboratory of Cardiac Energetics at the NHLBI. He is an exercise physiologist studying the molecular mechanisms of muscle energy conversion and power development. Dr. Glancy and his team won the Orloff Award for providing a better understanding of how potential energy is distributed across the muscle cell via a mitochondrial reticulum.

Joel Moss, M.D., Ph.D. is a senior investigator in the Cardiovascular and Pulmonary Branch at the NHLBI. His clinical trial work focuses on the pathogenesis of cystic lung diseases, such as lymphangioleiomyomatosis (LAM), a rare lung disease that mostly affects women of childbearing age. Dr. Moss and his team won the Orloff Award for demonstrating of the effects of therapy, hormonal status, and cell signaling pathways on the detection and characterization of circulating tumor cells in patients with LAM and tuberous sclerosis complex and in models of tumorigenesis.

Orloff Innovation Winners

Toren Finkel, M.D., Ph.D. and Team: For measuring the turnover of intact mitochondria in vivo

Michael S. Hansen, Ph.D. and Team: For work on open source tools provide high performance image reconstruction in a clinical environment

Warren J. Leonard, M.D. and Team: For work demonstrating a critical role for STAT1 in IL-21 signaling

Warren J. Leonard, M.D. and Team: For work describing the first partial agonists for a cytokine and their therapeutic potential

Keji Zhao, Ph.D. and Team: For work on development of single-cell Dnase-sequencing (scDNase-seq)