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NHLBI Small Business Program


The NHLBI Small Business Program enables US-owned and operated small businesses to engage in research and development on innovative and commercially promising products and services to prevent, diagnose, and treat heart, lung, and blood-related diseases and disorders.

Funding for small business research is available through the Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) mechanisms. For an overview of these mechanisms, please visit ABOUT THE PROGRAMS. You can also explore current NHLBI SBIR/STTR funding opportunities here.

Staff from the NHLBI Office of Translational Alliances and Coordination (OTAC), are available to advise and mentor NHLBI SBIR/STTR applicants and awardees on matters relating to product development, regulatory affairs, intellectual property, product commercialization, licensing, and strategic partnerships.

We strongly encourage prospective SBIR/STTR applicants to contact us to discuss their planned funding proposals. Please visit OTAC’s website to learn more about the services that our office offers.

Latest Announcements

Provide Input on NHLBI Translational Research


Responses due February 17, 2017

The NHLBI has released a Request for Information (NOT-HL-16-472) seeking comments on early translational research activities supported by the institute. The NHLBI seeks to facilitate and accelerate the development of new clinical interventions by bridging the gaps between mechanistic, discovery, and early translational research. This includes providing appropriate mechanisms to support investigator-initiated research, addressing resource and knowledge gaps, and creating initiatives to support career development of translational scientists and biomedical entrepreneurs.

The institute is seeking information on what you consider to be the major early translational needs of the NHLBI research community that could be addressed by NHLBI through grants, contracts, expertise, or resources.

For more information on how to respond, please read the full Notice: NOT-HL-16-472

Get Tips on Your Commercialization Plan and Regulatory Strategy

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Archives of What's New

Last Updated January 2017

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Tel: 301-496-2149

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NHLBI Small Biz Inquiry Form

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Upcoming Events

02/13 - 02/14 BIO CEO & Investor Conference external disclaimer - New York, NY

02/18 - 02/21 CRT17 external disclaimer - Washington, DC

03/09BD Boston Biotech Conference 2017 external disclaimer - Boston, MA

03/12 - 03/15AUTM 2017 Annual Meeting external disclaimer - Hollywood, FL

03/17 - 03/19American College of Cardiology (ACC. 17) external disclaimer - Washington, DC

03/23 - 03/25Venture Well external disclaimer - Washington, DC

03/30 - 03/31AdvaMed Innovation Summit external disclaimer - Washington, DC



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