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How and when do I submit my application?

How: NIH is in the process of converting systems to require Electronic Submission of all grant applications by September 2007. Applicants are encouraged to prepare themselves now to participate in electronic submission. offers step-by-step instructions for electronic submission of applications in Apply for Grants. NIH has training information on Electronic Submission of Grant Applications. You will also find SF424 Application and Electronic Submission Information on the OER website.

When: In general, most new clinical research grant applications have three receipt dates each year (See Submission Dates/Deadlines). This is unlike applications that are in response to a RFA, RFP or PA where a specific due date is delineated in the announcement.

CSR describes in detail the Submission and Assignment Process here.

Remember that applications that exceed $500,000 in direct costs in any year are subject to additional submission rules and may not simply be submitted to CSR without prior approval of NHLBI. If CSR receives such an application, it will be returned to you without review. (See "What if my project exceeds $500,000 in direct costs")

Multiple Principal Investigators is a new opportunity to formally allow more than one Principal Investigator ( PI ) on individual research awards particularly on projects that require a team approach. Read the information carefully to acquaint yourself with which mechanisms allow multiple investigators and how to indicate this in your grant application.

Page Last Updated: February 2011
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