Find NHLBI Clinical Trials

Search selected NHLBI-supported clinical trials and observational studies by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.

FILTER BY KEYWORD

Showing 1 - 10 out of 138 results
Recruiting
Are you 75 years old or older and interested in participating in a clinical trial where researchers are studying whether statins, which are often used to treat high cholesterol, can help improve heart and brain health. To participate, you cannot have cardiovascular disease or dementia. The study is taking place at locations in Alabama, Arizona, Arkansas, California, Connecticut, Florida, Georgia, Illinois, Indiana, Iowa, Kansas, Kentucky, Louisiana, Maine, Maryland, Massachusetts, Michigan, Minnesota, Mississippi, Missouri, Nebraska, Nevada, New York, North Carolina, Ohio, Pennsylvania, Rhode Island, South Carolina, Tennessee, Texas, Utah, Virginia, West Virginia, Wisconsin, and Puerto Rico.
Older Adult
Accepting Healthy Volunteers
Recruiting
Alabama
California
Maine
Does your child have obesity? In this study, children and teens, 7 to 13 years of age with obesity and their parents will learn about nutrition, behavior changes, and exercise through the Bright Bodies lifestyle program. Researchers want to see if this program can help lower weight gain and screen time, improve sleep, eating behaviors, and quality of life, and reduce parental stress. The study is taking place at locations in Alabama, California, and Maine.
Child
Recruiting
Are you an adult with atrial fibrillation? In this study, researchers are comparing a continuous direct oral anticoagulation (DOAC) use versus time-limited (1 month) DOAC guided by an AF-sensing Smart Watch (AFSW) for persons with atrial fibrillation and a moderate risk of stroke. Participants must be between the ages of 22 and 85 and have a history of atrial fibrillation. The study is taking place at locations in California, Colorado, Florida, Georgia, Illinois, Indiana, Iowa, Maine, Maryland, Massachusetts, Michigan, Minnesota, Missouri, New Jersey, New Mexico, New York, North Carolina, Ohio, Oklahoma, Pennsylvania, South Carolina, Texas, Virginia, Wisconsin, and Washington, D.C.
Adult, Older Adult
Recruiting
Do you have mitral valve disease? This clinical trial is testing different types of images taken of the heart to learn more about mitral valve disease and the best ways to treat it. You must be 60 years old to participate. The study is enrolling patients in locations in Arkansas, California, Georgia, Indiana, Louisiana, Maine, Maryland, Massachusetts, Michigan, Missouri, New York, North Carolina, Ohio, Pennsylvania, and Quebec City, Canada.
Adult, Older Adult
Recruiting
Did you develop atrial fibrillation after coronary artery bypass graft (CABG) surgery? Did you develop atrial fibrillation after a coronary artery bypass grafting (CABG) surgery? This study is looking at how well oral anticoagulation medicines work to prevent complications, such as blood clots and heart attack, for patients who experience post-operative atrial fibrillation (POAF). This study is in multiple locations around the country.
Adult, Older Adult
Recruiting
Are you 65 years old or older, and do you have severe primary mitral regurgitation? This condition — also called degenerative mitral regurgitation — happens when there is a problem with the mitral valve itself or its supporting tissue, leading to a leaky valve. This study is comparing the safety and effectiveness of two different ways of repairing the mitral valve: transcatheter edge-to-edge repair and surgical repair. To participate in this study, your healthcare provider must determine that you are a candidate for both mitral valve transcatheter edge-to-edge repair and surgical repair. This study takes place in multiple locations across the United States and Canada.
Older Adult
Recruiting
Maryland
Are you a healthy adult? In this clinical trial, researchers are trying to improve the quality of heart CT scans by using new methods to create the images. Researchers will take normal CT images of the heart and compare those images to super high-resolution images made with a super-computer. Healthy adults aged 18 years or older may be able to participate. The study is taking place at the NIH Clinical Center in Bethesda, Maryland.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
Maryland
Are you at least 18 years old and scheduled for a CT of the chest, abdomen, and pelvis? In this study, researchers want to learn if new CT imaging methods with less radiation make images that are similar to traditional ways. If you are at least 18 and your doctor has said you need a CT scan of the chest, abdomen, or pelvis, you may be able to participate. This study is taking place at the National Institutes of Health Clinical Center in Bethesda, Maryland.
Adult, Older Adult
Recruiting
Maryland
The goal of the study is to look at the relationship between how individuals with Sarcoidosis take the sarcoidosis medicines and how it affects the disease, to evaluate any factors that may make individuals not want to take the medicines, and to develop and refine ways to help support individuals with Sarcoidosis especially when it comes to the medicines. The overall hypothesis is higher medication adherence will be associated with better clinical outcomes in sarcoidosis. The investigators will enroll 150 patients with biopsy proven pulmonary sarcoidosis for at least one year who are on any oral treatment regimen for at least six months into a 12-month longitudinal study.
Adult, Older Adult
Recruiting
Maryland
Ohio
The purpose of this study is to see if adding a drug called Regadenoson to the EVLP circulation reservoir during perfusion of marginal donor lungs will help increase the likelihood that the donor lungs will become usable for transplantation.
Adult, Older Adult