Find NHLBI Clinical Trials

Search selected NHLBI-supported clinical trials and observational studies by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.

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Showing 1 - 10 out of 22 results
Recruiting
Are you scheduled for a stem cell transplant with cord blood? This study will assess the safety and effectiveness of certain cord blood transplants. The study will help researchers learn the best methods for collecting, storing, and using cord blood in transplants. To participate in this study, you must have a disorder that compromises your body’s ability to make blood cells. This study is located in Bethesda, Maryland.
All Ages
Recruiting
Do you want to help find new treatments for heart failure with preserved ejection fraction? This study is testing whether a medicine called spironolactone can help treat heart failure with preserved ejection fraction when paired with the standard treatment. Spironolactone helps to remove excess water and sodium from the body. To participate in this study, you must be between 50 and 99 years old and diagnosed with heart failure with preserved ejection fraction.
Adult, Older Adult
Recruiting
Do you have heart failure with preserved ejection fraction (HFPEF)? This study is testing the efficacy of a diuretic medicine called spironolactone that stops your body from absorbing too much salt and keeps your potassium levels from dropping too low. Participants of this study must be between 50 and 99 years old and already taking diuretic medicine. This study takes place in multiple locations across the United States and Sweden.
Adult, Older Adult
Recruiting
Iowa
Do you know someone whose child was just born preterm? This study aims to understand why some premature babies have low blood pressure by studying heart and lung changes during the first week of life in preterm babies who do or do not have low blood pressure. Researchers hope the results will improve monitoring of newborns’ blood circulation patterns. To participate in this study, your newborn must have weighed 2.2 pounds or less at birth, be less than 1 week old, and be receiving care in a neonatal intensive care unit. This study is located in Houston, Texas.
Child
Recruiting
Iowa
Do you live in Iowa and want to work with a pharmacist to manage your high blood pressure? This study will test a program that uses pharmacists to help people manage high blood pressure. You will be given a blood pressure monitor to take readings at home and text them to a pharmacist. You will then either talk to the pharmacist once or be part of the more intensive program where the pharmacist develops a care plan and monitors you for a year. To participate in this study, you must be older than 21, have had a systolic pressure greater than 145 mm Hg or diastolic pressure greater than 95 mm Hg at your previous clinic visit, and be a patient at the Family Medicine, River Crossings, Scott Blvd, or Muscatine University of Iowa Clinics. This study is located in Iowa.
Adult, Older Adult
Recruiting
Iowa
El objetivo de este estudio es comprender por qué algunos bebés prematuros tienen baja presión arterial mediante el estudio de los cambios en el corazón y los pulmones durante la primera semana de vida en los bebés prematuros que tienen presión arterial baja o no. Los investigadores esperan que los resultados mejoren el monitoreo de los patrones de circulación sanguínea de los recién nacidos. Para participar en este estudio, su recién nacido debe haber pesado 1 kilogramo (2,2 libras) o menos en el nacimiento, tener menos de 1 semana de edad y estar recibiendo atención en una unidad de cuidados intensivos neonatales. Este estudio se lleva a cabo en Houston (Texas).
Child
Recruiting
Iowa
Are you an adult with high blood pressure and currently a patient at the University of Iowa River Crossing, Family Medicine, or Scott Boulevard clinic? This study is exploring whether working closely with a pharmacist to monitor blood pressure can help improve symptoms of high blood pressure compared with infrequent discussions with a pharmacist via text and phone calls. To participate in this study, you must be between 21 and 100 years old. This study takes place in Iowa City, Iowa.
Adult, Older Adult
Recruiting
Are you a 30- to 55-year-old smoker or non-smoker who would like to support better understanding of COPD risk factors? This study aims to find early signs of COPD in adults who have a high risk of this condition. Researchers will compare results from questionnaires, lung tests, and other tests in people who smoke and in people who do not smoke to look for factors that predict which people will develop COPD. To participate in this study, you must either currently smoke or have no history of smoking. This study takes place in multiple locations in the United States.
Adult
Accepting Healthy Volunteers
Recruiting
Iowa
North Carolina
Ohio
Are you a healthy adult or an adult who has been diagnosed with an interstitial lung disease (ILD)? This study will test whether administering an inhaled gas called hyperpolarized 129Xe before magnetic resonance imaging (MRI) better detects changing disease activity. To participate in the study, you must be age 18 or older and have no history of smoking for the past 5 years. This study will take place in Iowa City, Iowa; Cincinnati, Ohio; and Durham, North Carolina.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
Have you had a heart attack, and do you want to help improve strategies for blood transfusion? The study is comparing two strategies for blood transfusions in heart attack patients who have anemia—whether to give a blood transfusion when the hemoglobin level is less than 10 g/dL, or to give blood only when the blood count is below 8 g/dL. To participate in this study, you must be at least 18 years old, have anemia, and be hospitalized for a heart attack. The study is located in New Brunswick, New Jersey.
Adult, Older Adult