Find NHLBI Clinical Trials

Search selected NHLBI-supported clinical trials and observational studies by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.

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Showing 1 - 10 out of 11 results
Recruiting
District Of Columbia
Were you or your child recently diagnosed with VTE? This study is testing a six-week course of blood-thinning medicines for the treatment of venous thromboembolisms (VTE) to see if they are as effective as the standard treatment course of three months. To participate in this study, you or your child must be younger than 21 years old. This study has 54 locations in Alabama, Arizona, California, Connecticut, Florida, Georgia, Illinois, Indiana, Kentucky, Maryland, Massachusetts, Michigan, Missouri, New Jersey, New York, North Carolina, Ohio, Oklahoma, Oregon, Pennsylvania, South Carolina, Texas, Utah, Virginia, Wisconsin, Australia, Austria, Canada, Israel, and the Netherlands.
Child, Adult
Recruiting
District Of Columbia
Maryland
Do you or your child have sickle cell disease or sickle cell trait? This study is interested in understanding pain crises and lung complications that occur in sickle cell disease patients and patients who have other red blood cell disorders. To participate in this study, you must be at least 2 years old with known or suspected sickle cell disease, sickle cell trait, or other red blood cell disorders. Participants will have a physical exam and receive standard medical care for sickle cell disease, including routine follow-up tests and procedures. This study is located in Washington, D.C., and Bethesda, Maryland.
All Ages
Recruiting
Do you or your child have severe sickle cell disease and also know a half-matched bone marrow donor? This study is seeking to improve bone marrow transplantation success from half-matched donors by testing a different conditioning procedure that uses a variety of medicines to prepare for the transplant. To participate in this study, you must be 15 to 45 years old and have severe sickle cell disease or have a child 5 to 14 years old who has had a stroke. This study is located in many sites across the United States, including Miami, Florida, and St. Louis, Missouri.
Child, Adult
Recruiting
Are you scheduled for a stem cell transplant with cord blood? This study will assess the safety and effectiveness of certain cord blood transplants. The study will help researchers learn the best methods for collecting, storing, and using cord blood in transplants. To participate in this study, you must have a disorder that compromises your body’s ability to make blood cells. This study is located in Bethesda, Maryland.
All Ages
Recruiting
Do you want to help find new treatments for heart failure with preserved ejection fraction? This study is testing whether a medicine called spironolactone can help treat heart failure with preserved ejection fraction when paired with the standard treatment. Spironolactone helps to remove excess water and sodium from the body. To participate in this study, you must be between 50 and 99 years old and diagnosed with heart failure with preserved ejection fraction.
Adult, Older Adult
Recruiting
District Of Columbia
Maryland
Are you able to have a magnetic resonance imaging (MRI) scan and want to help people with heart failure? This study is developing new methods for imaging the heart and blood vessels using MRI to improve how healthcare providers diagnose people with heart failure. This study takes place in Maryland and Washington, DC.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
District Of Columbia
Maryland
Are you a healthy adult woman living in Washington, DC, and interested in helping researchers learn about heart disease? This study is exploring differences in stress and exercise habits among women who live in different areas of the city. To participate in this study, you must be a healthy woman between the ages of 19 and 45 living in Washington, DC, wards 3 or 5 with access to a smartphone. This study takes place in Washington, DC, and Maryland.
Adult, Older Adult
Accepting Healthy Volunteers
Female
Recruiting
Do you or your child have dilated cardiomyopathy? This study aims to investigate the genetic causes of dilated cardiomyopathy to improve early diagnosis and prevention. To participate in this study, you or your child can be any age but must have dilated cardiomyopathy. This study takes place at multiple locations across the United States.
All Ages
Recruiting
Do you have heart failure with preserved ejection fraction (HFPEF)? This study is testing the efficacy of a diuretic medicine called spironolactone that stops your body from absorbing too much salt and keeps your potassium levels from dropping too low. Participants of this study must be between 50 and 99 years old and already taking diuretic medicine. This study takes place in multiple locations across the United States and Sweden.
Adult, Older Adult
Recruiting
Are you or your child between the ages of 3 and 21 and experiencing pain episodes? This study tests a treatment called arginine therapy for pain episodes in children with sickle cell disease. Researchers are investigating how safe and effective this treatment is, as well as how arginine is metabolized in the body and its effects on cells. To participate in this study, you or your child must have sickle cell disease and pain that requires medical attention. This study takes place in multiple locations in the United States.
Child, Adult