Find NHLBI Clinical Trials

Search selected NHLBI-supported clinical trials and observational studies  by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.

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Showing 1 - 10 out of 46 results
Recruiting
Delaware
Are you approaching menopause? Heart disease is the leading cause of death in women, and deaths from heart disease among women 35 to 54 years old are increasing. Researchers are studying changes in health caused by menopause to learn whether estradiol, a medication commonly given to women during menopause, can help improve health. You may be able to participate if you are a woman between 40 and 58 years old. The study is taking place in Newark, Delaware.
Adult
Accepting Healthy Volunteers
Female
Recruiting
Have you or your child been diagnosed with a blood disorder? If so, you (or they) may be able to participate in a clinical study where researchers are studying a type of infusion using cord blood. Participants can be of any age but must have a blood disorder diagnosed by their doctor. The study is taking place in locations in Alabama, Arizona, California, Colorado, Delaware, Florida, Georgia, Illinois, Indiana, Kentucky, Maryland, Massachusetts, Michigan, Minnesota, Mississippi, Missouri, Nebraska, New York, Ohio, Oklahoma, Oregon, Pennsylvania, South Carolina, Tennessee, Texas, Virginia, Washington, Washington, D.C., West Virginia, and Wisconsin.
All Ages
Recruiting
Are you scheduled for a stem cell transplant with cord blood? This study will assess the safety and effectiveness of certain cord blood transplants. The study will help researchers learn the best methods for collecting, storing, and using cord blood in transplants. To participate in this study, you must have a disorder that compromises your body’s ability to make blood cells. This study is located in Bethesda, Maryland.
All Ages
Recruiting
DIVA is a pragmatic randomized clinical trial (RCT) to determine: among (P) preterm infants born 24-27 6/7 weeks gestation undergoing extubation from mechanical ventilation, whether (I) Non-invasive neurally adjusted ventilatory assist (NIV-NAVA) (C) compared with Non-synchronized nasal intermittent positive pressure ventilation (NS-NIPPV), will reduce the incidence of (O) extubation failure within (T) 5 days (120 hours) of extubation.
Child
Recruiting
Are you 75 years old or older and interested in participating in a clinical trial where researchers are studying whether statins, which are often used to treat high cholesterol, can help improve heart and brain health. To participate, you cannot have cardiovascular disease or dementia. The study is taking place at locations in Alabama, Arizona, Arkansas, California, Connecticut, Florida, Georgia, Illinois, Indiana, Iowa, Kansas, Kentucky, Louisiana, Maine, Maryland, Massachusetts, Michigan, Minnesota, Mississippi, Missouri, Nebraska, Nevada, New York, North Carolina, Ohio, Pennsylvania, Rhode Island, South Carolina, Tennessee, Texas, Utah, Virginia, West Virginia, Wisconsin, and Puerto Rico.
Older Adult
Accepting Healthy Volunteers
Recruiting
Are you an adult female with LAM? If so, you may be able to participate in this clinical study where researchers are observing patients who are taking or have taken a certain kind of medication, mammalian target of rapamycin (mTOR), to treat lymphangioleiomyomatosis, also known as LAM. You must be at least 18 years old to take part. The study is taking place at locations in California, Colorado, Florida, Georgia, Illinois, Massachusetts, Michigan, Minnesota, Missouri, New York, Ohio, Oregon, Pennsylvania, South Carolina, Tennessee, Texas, Utah, and Washington.
Adult, Older Adult
Female
Recruiting
Missouri
The overall goal is to assess the potential of the radiotracer to track inflammatory cells in lung diseases.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
The goal of this clinical trial is to compare different types of blood transfusions for critically injured patients who require large-volume blood transfusions. Participants must be at least 15 years old and need a massive blood transfusion. The study is taking place in locations in Alabama, California, Louisiana, Maryland, Missouri, North Carolina, Ohio, Oregon, Pennsylvania, Texas, Washington, and Wisconsin.
All Ages
Recruiting
Missouri
Nebraska
Are you interested in participating in clinical research about ultrasounds? Ultrasounds are one of the most common ways to take images of the inside of your body. In some cases, something called a contrast agent is injected through an IV to make your organs even more visible during the ultrasound. Researchers in this clinical trial are comparing a new type of contrast agent to the current type used in ultrasounds. Participants must be 19 years old and considered to be generally healthy. The study is taking place in Kansas City, Missouri, and Omaha, Nebraska.
Adult, Older Adult
Accepting Healthy Volunteers