Find NHLBI Clinical Trials

Search selected NHLBI-supported clinical trials and observational studies by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.

FILTER BY KEYWORD

Showing 1 - 9 out of 9 results
Recruiting
Tennessee
Have you been diagnosed with orthostatic intolerance? This study aims to find out how the body’s regulation of basic functions, such as heart rate and blood pressure, is altered in people who have orthostatic intolerance. This condition, which has an unknown cause, is characterized by a racing heartbeat, dizziness, lightheadedness, and other symptoms that occur when a person stands up. To participate in this study, you must be between 18 and 80 years old and have orthostatic intolerance. This study is located in Nashville, Tennessee.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
Iowa
Do you know someone whose child was just born preterm? This study aims to understand why some premature babies have low blood pressure by studying heart and lung changes during the first week of life in preterm babies who do or do not have low blood pressure. Researchers hope the results will improve monitoring of newborns’ blood circulation patterns. To participate in this study, your newborn must have weighed 2.2 pounds or less at birth, be less than 1 week old, and be receiving care in a neonatal intensive care unit. This study is located in Houston, Texas.
Child
Recruiting
Iowa
El objetivo de este estudio es comprender por qué algunos bebés prematuros tienen baja presión arterial mediante el estudio de los cambios en el corazón y los pulmones durante la primera semana de vida en los bebés prematuros que tienen presión arterial baja o no. Los investigadores esperan que los resultados mejoren el monitoreo de los patrones de circulación sanguínea de los recién nacidos. Para participar en este estudio, su recién nacido debe haber pesado 1 kilogramo (2,2 libras) o menos en el nacimiento, tener menos de 1 semana de edad y estar recibiendo atención en una unidad de cuidados intensivos neonatales. Este estudio se lleva a cabo en Houston (Texas).
Child
Recruiting
Tennessee
Do you have low blood pressure due to primary autonomic failure from a medical condition such as Parkinson disease, multiple system atrophy, or pure autonomic failure? Autonomic failure is caused by problems with a part of the nervous system called the autonomic nervous system. People with this condition can suffer debilitating low blood pressure upon standing. This study is testing the use of compression garments compared with a medicine called midodrine to improve blood pressure. To participate in this study, you must be between 18 and 80 years old and have low blood pressure when standing. This study takes place in Nashville, Tennessee.
Adult, Older Adult
Recruiting
New York
Do you or your child have a platelet, bleeding, or white blood cell disorder? This study is looking at people who have platelet or other blood disorders. The researchers will use a blood sample to look for problems with platelets and a possible genetic cause in the participant’s DNA or RNA. To participate in this study, you must be a child or adult who either is healthy or has a platelet disorder, coagulation disorder, or white blood cell disorder. This study is located in New York, New York.
All Ages
Accepting Healthy Volunteers
Recruiting
Massachusetts
Does your infant have a low platelet count? This study is investigating the safety and efficacy of platelet transfusion as a treatment for infants with thrombocytopenia. Researchers are looking at the positive effects of platelet transfusion against the negative effects, such as the release of inflammatory molecules and the formation of blood clots. To participate in this study, your child must be younger than 6 months old and have a low platelet count (less than 100 × 109/L). This study takes place in Boston, Massachusetts.
Child
Recruiting
Massachusetts
Utah
Does your infant have a low platelet count? This study investigates immature platelet counts as a marker for bleeding risk in newborns with thrombocytopenia, compared with platelet counts alone. Immature platelets are the most recently produced platelets and may be a better marker of platelet production. To participate in this study, you must have a newborn who is less than 32 weeks’ gestational age, has a birth weight greater than 500 grams, and has a platelet count less than 100 × 109/L. This study takes place in multiple locations in the United States, the Netherlands, and Sweden.
All Ages
Recruiting
Utah
Are you an adult with polycythemia vera or thrombocytosis? This study aims to find a new treatment or cure for polycythemia vera and thrombocytosis by locating genes and their changes, or mutations, that may contribute to these disorders. To participate in this study, you must have polycythemia vera with elevated hemoglobin (higher than 18 in men and 16 in women) or thrombocytosis with an elevated platelet count (higher than 450,000). This study takes place in Salt Lake City, Utah.
All Ages
Recruiting
Minnesota
Are you a Minnesota resident with hypertrophic cardiomyopathy? This study aims to find out how common it is for people with hypertrophic cardiomyopathy to also have sleep apnea. Hypertrophic cardiomyopathy is a disease that causes the heart muscle to thicken. Participants will also wear a heart rhythm monitor to help researchers learn whether sleep apnea is linked to arrhythmia. The study seeks healthy volunteers as well as participants in the Hypertrophic Cardiomyopathy Registry. To participate in this study, you must not have had a catheter ablation procedure to treat atrial fibrillation, had surgery to replace your heart valves, or been treated for sleep apnea. The study is located in Rochester, Minnesota.
Adult, Older Adult
Accepting Healthy Volunteers