Find NHLBI Clinical Trials

Search selected NHLBI-supported clinical trials and observational studies by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.

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Showing 21 - 30 out of 31 results
Recruiting
North Carolina
Are you an adult with both asthma and obesity? This study is testing whether a medicine called L-citrulline can help treat asthma and improve lung function in people who have obesity. To participate in this study, you must be 18 to 65 years old and have asthma and obesity. This study takes place in Durham, North Carolina.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
Rhode Island
Are you an adult with obesity and at high risk of heart and blood vessel disease? This study is testing a new program to help people who have obesity stick to their healthy eating plan. Researchers from this study are developing a program that will predict when participants are most likely to stop making healthy food choices and will send messages to remind participants of their weight loss goals. To participate in this study, you must be 18 to 70 years old, have overweight or obesity, and be at high risk of heart and blood vessel diseases. This study takes place in Providence, Rhode Island.
Adult, Older Adult
Recruiting
Illinois
Are you between 18 and 50 and have obesity? This study is examining whether obesity causes chemical changes to DNA that affect the amounts of certain proteins that your body makes. These changes in protein levels may raise the risk of heart and blood vessel diseases in people who have obesity. The study will test whether regular physical activity and weight loss surgery can help reverse these changes to DNA. This study takes place in Chicago, Illinois.
Adult
Accepting Healthy Volunteers
Recruiting
South Carolina
Does your child have overweight or obesity? This study is testing whether a treatment program called FIT Families can help treat obesity in African American teenagers. FIT Families is a 6-month family-based program that involves home visits by community health workers. Participants in this study must be 12 to 17 years old, African American, and diagnosed with obesity. This study is located in South Carolina.
All Ages
Recruiting
Minnesota
Are you an adult with sleep apnea, overweight, or obesity, or do you just want to help research? This study is looking at how sleep apnea changes fat tissue in the body. The researchers will examine whether these changes in fat tissue may raise the risk of heart and blood vessel diseases. To participate in this study, you must be between 18 and 60 years old with obstructive sleep apnea and healthy without any chronic diseases. This study takes place in Rochester, Minnesota.
Adult
Accepting Healthy Volunteers
Recruiting
Pennsylvania
Rhode Island
Does your child have overweight or obesity or just want to be in a study on sleep and eating habits? Overweight and obesity are common in children who do not get enough good quality sleep. This study aims to understand how sleep deficiency can affect a child’s ability to make good food choices. Researchers will ask participants to spend either 8 or 11 hours in bed and to keep track of their food choices. Participants in this study must be 8 to 12 years old. This study takes place in Pittsburgh, Pennsylvania and Providence, Rhode Island.
Child
Accepting Healthy Volunteers
Recruiting
Massachusetts
Pneumonia is a major public health problem for the elderly and is one of the leading causes of hospitalization and death for this population, particularly for elderly nursing home residents. This planning grants seeks to establish a safe and effective dose of zinc supplementation with the goal to conduct a larger randomized clinical trial to study the effect of zinc supplementation in nursing home elderly with low serum zinc levels on the risk, antibiotic use, and duration of sick days with pneumonia. This project has significant potential to positively impact the health and quality of life in the elderly and to reduce the economic costs associated with their care.
Older Adult
Accepting Healthy Volunteers
Recruiting
Do you or a loved one have pneumonia? This study will test whether combining two medicines to reduce inflammation of the airway and to keep it open may help prevent respiratory failure in people who have pneumonia. To participate in this study, you must be at least 18 years old and have severe pneumonia with low blood oxygen levels.
Adult, Older Adult
Recruiting
Do you have symptoms of a lung disease (such as long-term wet cough, bronchiectasis, or recurrent pneumonia) with no genetic diagnosis? This study aims to develop new ways to diagnose primary ciliary dyskinesia (PCD) or primary immune deficiency (PID), two conditions that can have similar symptoms. Researchers will combine information from genetic testing, lung imaging, and lung function tests to diagnose and tell the difference between these two conditions. Participants in this study must be 5 to 45 years old and must have symptoms of a serious lung disease but no diagnosis. This study is taking place at multiple locations in the United States and in Canada, including the NIH Clinical Center in Bethesda, Maryland.
Child, Adult