Clinical Trials

Are you an adult whose high blood pressure does not improve with lifestyle changes and medicines? This study will assess whether minocycline, an antibiotic with anti-inflammatory effects, can improve blood pressure control in patients who do not respond to medicines in combination with lifestyle changes, such as physical activity, weight loss, and healthy eating patterns. To participate you must be at least 18 years old and have high blood pressure that does not respond to treatment with three different high blood pressure medicines even when used at the maximum doses. Please note that this study is in Gainesville, Florida.

Do you or a loved one have pneumonia? This study will test whether combining two medicines to reduce inflammation of the airway and to keep it open may help prevent respiratory failure in people who have pneumonia. To participate in this study, you must be at least 18 years old and have severe pneumonia with low blood oxygen levels.

Are you an adult who does not have high blood pressure and is interested in research? This study will investigate how the brain regulates the body’s response to stress and how infection with HIV or pre-hypertension affects regulation. Your heart and brain activity will be measured while you are at rest, during a mentally stressful task, and while you feel angry. The study will also test whether a breathing exercise improves regulation. People with and without HIV and pre-hypertension will be included. To participate in this study, you must be between 21 and 65 years old and not have high blood pressure. This study is located in Miami, Florida.

Are you pregnant and also diagnosed with high blood pressure? This study aims to study the benefits and risks of medicine to treat pregnant women who have mild high blood pressure (

Are you an adult with high blood pressure? Some people with high blood pressure that does not respond well to medicine have a condition called neurogenic hypertension. This condition occurs when the nervous system becomes dysregulated as a result of high blood pressure. This study is examining the use of a new medicine to treat this condition called minocycline. To participate in this study, you must be between 18 and 85 years old and currently taking medicine to treat your high blood pressure. This study takes place in Gainesville, Florida.