Clinical Trials and Studies

Are you interested in helping researchers learn more about how inflammation and diseases of the blood vessels start? Diseases related to the immune system, blood clots, and blood vessels are interrelated. This study is trying to understand how these diseases start and what happens in the different organs in people with these diseases. To participate in this study, you or your child should be 5 years old or older and be healthy or have an autoimmune disease, or problems with blood clots or blood vessels. This study is in Bethesda, Maryland.

Do you have symptoms of a lung disease (such as long-term wet cough, bronchiectasis, or recurrent pneumonia) with no genetic diagnosis? This study aims to develop new ways to diagnose primary ciliary dyskinesia (PCD) or primary immune deficiency (PID), two conditions that can have similar symptoms. Researchers will combine information from genetic testing, lung imaging, and lung function tests to diagnose and tell the difference between these two conditions. Participants in this study must be 5 to 45 years old and must have symptoms of a serious lung disease but no diagnosis. This study is taking place at multiple locations in the United States and in Canada, including the NIH Clinical Center in Bethesda, Maryland.

Have you received treatment from a doctor for COPD that has gotten worse and have you been referred for pulmonary rehabilitation, which can help ease the symptoms of COPD.? In this study, researchers are comparing two ways to encourage people to participate in pulmonary rehabilitation. Participants must be at least 40 years old and be willing to participate in calls with a peer coach and view videos. The study is taking place in Springfield, Massachusetts.

Does your child have pulmonary arterial hypertension (PAH)? This study is testing if an app can help children with PAH be more physically active and increase their step count. To participate in this study, your child should be 13 to 19 years old and have PAH.