Clinical Trials

Are you between 65 and 85 years old and are a patient at Stanford? This study will evaluate the effect of an electronic health record (EHR) screening tool on rates of new noninvasive testing, diagnosis, and treatment of peripheral artery disease (PAD) over a 6-month period. The EHR-based screening tool will generate a group of patients at the highest risk of having undiagnosed PAD to participate in the study. To participate in this study, you must be between 65 and 85 years old, have at least 1 year of data with the Stanford EHR, and have no prior diagnosis of PAD. This study takes place in Palo Alto, California.

The investigators' central hypothesis is that early combination therapy with two PAH-specific oral therapies that have been shown to be well tolerated in the pediatric population, sildenafil and bosentan, will result in better World Health Organization (WHO) functional class at 12 months after initiation of PAH treatment than therapy with sildenafil alone.

Do you or your child have pulmonary hypertension and want to help research? This study is looking to better understand pulmonary hypertension in children who have this condition. To participate in this study, you or your child must be 21 years old or younger and must have been diagnosed with pulmonary hypertension before the age of 18. This study is located at multiple sites across the United States and Canada, including California, Colorado, Massachusetts, New York, Pennsylvania, Tennessee, and Alberta, Canada.