Find NHLBI Clinical Trials

Search selected NHLBI-supported clinical trials and observational studies by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.

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Showing 1 - 10 out of 36 results
Recruiting
Florida
Are you an adult who does not have high blood pressure and is interested in research? This study will investigate how the brain regulates the body’s response to stress and how infection with HIV or pre-hypertension affects regulation. Your heart and brain activity will be measured while you are at rest, during a mentally stressful task, and while you feel angry. The study will also test whether a breathing exercise improves regulation. People with and without HIV and pre-hypertension will be included. To participate in this study, you must be between 21 and 65 years old and not have high blood pressure. This study is located in Miami, Florida.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
Do you have a high-risk pregnancy? This study will investigate the use of a non-invasive scan called fetal magnetocardiography to detect potential problems in the fetus in five high-risk pregnancy conditions associated with stillbirth. The scan is normally used to look at fetal heart rhythms. To participate in this study, you must be at least 18 years old and pregnant with one of the following: having a stillbirth in a previous pregnancy, carrying identical twins, or having a fetus that has been diagnosed with major congenital heart disease, fetal hydrops, or fetal gastroschisis. This study takes place in Madison and Milwaukee, Wisconsin.
Female
Recruiting
Indiana
Are you a woman who is postmenopausal or a man older than 65? This study will investigate the effects of oral progesterone for older women and testosterone for older men on QT intervals. QT intervals that are increased by medicine can lead to dangerous heart rhythm problems. Researchers hope to learn more about why this happens and how to deliver safer doses. This study is located in Indianapolis, Indiana.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
Maryland
Do you have a heart or blood vessel disease, such as peripheral artery disease? This study aims to collect data and samples from people who have a heart or blood vessel disease. This may include blood tests, ultrasound exams, and heart and lung tests. Family members and healthy people may also participate. The results may help researchers better understand PAD and other heart and blood vessel diseases. Participants must be at least 2 years old. Women who are pregnant may not take part in some study activities. This study is located in Bethesda, Maryland.
All Ages
Accepting Healthy Volunteers
Recruiting
Maryland
Do you or a first-degree relative have a condition that raises the risk of heart disease? This study aims to test the heart and lung function of people who have a genetic or metabolic disease that raises their risk of heart disease. Participants in this study must be between 2 and 100 years old. This study is located in Bethesda, Maryland.
All Ages
Accepting Healthy Volunteers
Recruiting
Georgia
Are you an adult who has PAD and difficulty walking? This study is testing whether a medicine that helps the body make more white blood cells can, along with walking exercise, improve symptoms and blood flow in people who have PAD. To participate in this study, you must be between 21 and 80 years old and have PAD. Women must not be pregnant and must use birth control or have been surgically sterilized if they still have menstrual periods. This study is located in Atlanta, Georgia.
Adult, Older Adult
Recruiting
Illinois
Are you an adult who has PAD and overweight or obesity? This study aims to learn whether participating in an exercise program with a weight loss program reduces PAD signs and symptoms more than an exercise program alone. To participate, you must be between 18 and 85 years old, have PAD, and have a body mass index (BMI) greater than 28 but less than 45. Participants must also be willing to use a smartphone and attend weekly study sessions. This study is located in Evanston, Illinois; New Orleans, Louisiana; and Minneapolis, Minnesota.
Adult, Older Adult
Recruiting
Maryland
Do you or your child have sickle cell disease and have a stem cell donor? This study is exploring how to improve bone marrow transplant procedures so the body better accepts donor stem cells. Participants in this study must be at least 4 years old. This study is located in Bethesda, Maryland.
All Ages
Accepting Healthy Volunteers
Recruiting
Maryland
Do you or your child have sickle cell disease or sickle cell trait? This study is interested in understanding pain crises and lung complications that occur in sickle cell disease patients and patients who have other red blood cell disorders. To participate in this study, you must be at least 2 years old with known or suspected sickle cell disease, sickle cell trait, or other red blood cell disorders. Participants will have a physical exam and receive standard medical care for sickle cell disease, including routine follow-up tests and procedures. This study is located in Washington, D.C., and Bethesda, Maryland.
All Ages
Recruiting
Tennessee
Are you between 16 and 20 years old and willing to answer questions about managing your sickle cell disease? This study is investigating the care and quality of life of patients who have sickle cell disease as they transition from pediatric to adult care. To participate in this study, you must be between 16 and 20 years old and be a patient of St. Jude Children’s Research Hospital. This study is located in Memphis, Tennessee.
Child, Adult